Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 5/20 | 0.38 |
| ▸ | NPY4R | P50391 | 7/20 | 0.38 |
| ▸ | NPY1R | P25929 | 4/20 | 0.38 |
| ▸ | NPY2R | P49146 | 2/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.37 |
| ▸ | NPPA | P01160 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | GRB2 | P62993 | 3/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498619 | 0.79 | LAP3 (0.42) | ECE1ITGB1ITGA4 | |
| SCHEMBL9500894 | 0.79 | LAP3 (0.42) | ECE1ITGB1ITGA4 | |
| SCHEMBL9500536 | 0.79 | LAP3 (0.42) | ECE1ITGB1ITGA4 | |
| SCHEMBL9500855 | 0.78 | LAP3 (0.41) | ECE1ITGB1ITGA4 | |
| SCHEMBL9500612 | 0.77 | LAP3 (0.42) | ACEITGB1ITGA4 | |
| SCHEMBL29674608 | 0.76 | FNTA (0.50) | NPY4RNPY1RNPY2RNPY5RITGB3 | |
| SCHEMBL21570265 | 0.76 | FNTA (0.50) | NPY4RNPY1RNPY2RNPY5RITGB3 | |
| SCHEMBL21570230 | 0.75 | NPY4R (0.55) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7435218 | 0.75 | NPY4R (0.55) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7435202 | 0.75 | NPY4R (0.55) | NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0333000-B1 | PEPTIDES WITH INHIBITORY ACTIVITY OF ENZYMATIC SYSTEMS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.p.A. (IT) | 1993-05-19 | — | — | EP | disclosed |
| EP-0333000-A2 | Peptides with inhibitory activity of enzymatic systems, process for their preparation and pharmaceutical compositions containing them | ZAMBON GROUP S.p.A. (IT) | 1989-09-20 | — | — | EP | disclosed |