SCHEMBL9501089

SCHEMBL9501089

C=C(c1ccccc1)C(C)(C)[SiH3]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.38
MAPT P10636 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
LMNA P02545 1/20 0.38
XBP1 P17861 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
ALDH1A1 P00352 4/20 0.36
TSHR P16473 3/20 0.36
HSD17B10 Q99714 1/20 0.36
GAA P10253 1/20 0.35
SRC P12931 1/20 0.35
CES2 O00748 3/20 0.35
CES1 P23141 3/20 0.35
DAO P14920 1/20 0.35
NAPRT Q6XQN6 1/20 0.35
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL965081 0.80 ATM (0.40) ATMMAPTMEN1KMT2ALMNA
SCHEMBL9651822 0.79 TSHR (0.31) TSHR
SCHEMBL7545115 0.78 SRC (0.41) ATMMAPTMEN1KMT2ALMNA
SCHEMBL22155799 0.76 EGFR (0.38) ATMMAPTMEN1KMT2ALMNA
SCHEMBL22157975 0.76 CES1 (0.43) ATMMAPTMEN1KMT2ALMNA
SCHEMBL11133993 0.74 CES1 (0.34) ATMMAPTMEN1KMT2ALMNA
SCHEMBL4789184 0.74 MAPT (0.48) ATMMAPTMEN1KMT2ALMNA
SCHEMBL9651770 0.74 ALDH1A1 (0.44) MAPTMEN1KMT2ATDP1ALDH1A1
SCHEMBL2987791 0.73 ELANE (0.47) ATMMAPTLMNAXBP1SMN1; SMN2
SCHEMBL2401292 0.73 RIPK1 (0.42) ATMMAPTMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0375079-B1 ALKENYLPHOXYLIMIDE MODIFIED POLYIMIDE Technochemie GmbH - Verfahrenstechnik (DE) 1993-06-09 EP disclosed
US-5120824-A Molding materials based on unsaturated monomers containing imide groups; engineering thermoplastics; toughness; heat resistance TECHNOCHEMIE GMBH VERFAHRENSTECHNIK (DE) 1992-06-09 US disclosed
EP-0469684-A1 Polyimide compositions SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-02-05 EP disclosed
US-4981934-A Curable composition comprising bis-imide and bis-(alkenyl phenol) TECHNOCHEMIE GMBH VERFAHRENSTECHNIK (DE) 1991-01-01 US disclosed
EP-0375079-A2 Alkenylphoxylimide modified polyimide Technochemie GmbH - Verfahrenstechnik (DE) 1990-06-27 EP disclosed
EP-0355926-A2 Alkenyl-modified polyimides Technochemie GmbH - Verfahrenstechnik (DE) 1990-02-28 EP disclosed
US-4035345-A Thermosetting bis-imide compositions RHONE-POULENC S.A. (FR) 1977-07-12 US disclosed