SCHEMBL7545115

SCHEMBL7545115

C=C(c1ccccc1)C(C)(C)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.41
ATM Q13315 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
XBP1 P17861 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TDP1 Q9NUW8 2/20 0.38
ALDH1A1 P00352 3/20 0.38
TSHR P16473 3/20 0.38
HSD17B10 Q99714 1/20 0.38
GAA P10253 1/20 0.36
CES2 O00748 3/20 0.36
CES1 P23141 3/20 0.36
DAO P14920 1/20 0.36
NAPRT Q6XQN6 1/20 0.36
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL965081 0.82 ATM (0.40) SRCATMMEN1KMT2ALMNA
SCHEMBL25912437 0.80 ATM (0.39) SRCATMMEN1KMT2ALMNA
SCHEMBL22155799 0.78 EGFR (0.38) SRCATMMEN1KMT2ALMNA
SCHEMBL9501089 0.78 ATM (0.38) SRCATMMEN1KMT2ALMNA
SCHEMBL22157975 0.78 CES1 (0.43) SRCATMMEN1KMT2ALMNA
SCHEMBL9867851 0.78 SRC (0.44) SRCATMLMNAMAPTXBP1
SCHEMBL18545987 0.76 HDAC1 (0.47) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL4789184 0.76 MAPT (0.48) ATMMEN1KMT2ALMNAMAPT
SCHEMBL12066324 0.75 CES1 (0.41) SRCATMMEN1KMT2ALMNA
SCHEMBL6067661 0.75 ATM (0.44) SRCATMLMNAMAPTXBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114853804-B Method for synthesizing high-regioselectivity alpha-alkenyl stannane by hydrogenating terminal alkyne stannum marshi 浙江大学 2024-07-05 CN disclosed
CN-114853804-A Method for synthesizing high-regioselectivity alpha-alkenyl stannane by hydrogenation of terminal alkyne martensitic tin 浙江大学 2022-08-05 CN disclosed
US-10195831-B2 Adhesive film and method of manufacturing the same and display device including the adhesive film SAMSUNG DISPLAY CO., LTD. (KR) 2019-02-05 US disclosed
WO-2016029439-A1 ORGANOSILICON MODIFIED PHOTOINITIATOR AND PHOTO-CURABLE ADHESIVE COMPOSITION THEREOF HENKEL (CHINA) COMPANY LIMITED (CN) 2016-03-03 WO disclosed
WO-2015030151-A1 CURABLE COMPOSITION FOR PHOTOIMPRINT AND METHOD OF PRODUCING FILM, OPTICAL COMPONENT, CIRCUIT BOARD, OR ELECTRONIC COMPONENT USING THE COMPOSITION CANON KABUSHIKI KAISHA (JP) 2015-03-05 WO disclosed
US-20150010766-A1 ADHESIVE FILM AND METHOD OF MANUFACTURING THE SAME AND DISPLAY DEVICE INCLUDING THE ADHESIVE FILM SAMSUNG DISPLAY CO., LTD. (KR) 2015-01-08 US disclosed
US-20150010766-A1 ADHESIVE FILM AND METHOD OF MANUFACTURING THE SAME AND DISPLAY DEVICE INCLUDING THE ADHESIVE FILM SAMSUNG DISPLAY CO., LTD. (KR) 2015-01-08 US disclosed
WO-2014006141-A1 RADIATION-CURABLE ACRYLATE-BASED INK-JET PRINTING INK HAPA AG (CH) 2014-01-09 WO disclosed
US-20100121048-A1 Cyclic Amine Compound and Use Thereof for the Prophylaxis or Treatment of Hypertension TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-05-13 US disclosed
EP-0945420-B1 Process for the preparation of bisphenols MITSUI CHEMICALS INC (JP) 2002-06-12 EP disclosed
US-6316677-B1 REACTING PHENOLIC COMPOUND WITH DIALKYLBENZENE, BIS(HYDROXYALKYL)BENZENE, OR (HYDROXYALKYL)-ALKENYLBENZENE; NEUTRALIZATION USING ANION EXCHANGE RESIN; CONCENTRATION, ISOLATION MITSUI CHEMICALS, INC. (JP) 2001-11-13 US disclosed
EP-0945420-A1 Process for the preparation of bisphenols Mitsui Chemicals, Inc. (JP) 1999-09-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100121048-A1 Cyclic Amine Compound and Use Thereof for the Prophylaxis or Treatment of Hypertension REN, AGTR1, AGTR2 SRC 967/4885ATM 2412/4885MEN1 750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.