Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499984 | 0.91 | HDAC9 (0.42) | KDM1AHDAC9 | |
| SCHEMBL1333907 | 0.78 | KDM1A (0.47) | KDM1AMEN1KMT2AAKR1B1CYP1A2 | |
| SCHEMBL5474666 | 0.76 | KDM1A (0.43) | KDM1AHDAC9MEN1KMT2AAKR1B1 | |
| SCHEMBL11079679 | 0.75 | KDM1A (0.45) | KDM1AMEN1KMT2AAKR1B1CYP1A2 | |
| SCHEMBL9499543 | 0.75 | SOAT1 (0.53) | MEN1KMT2A | |
| SCHEMBL19130231 | 0.74 | KDM1A (0.47) | KDM1AMEN1KMT2AAKR1B1CYP1A2 | |
| SCHEMBL6691850 | 0.74 | KDM1A (0.47) | KDM1AMEN1KMT2AAKR1B1CYP1A2 | |
| SCHEMBL7960703 | 0.74 | KDM1A (0.44) | KDM1AMEN1KMT2AAKR1B1CYP1A2 | |
| SCHEMBL10637900 | 0.73 | KDM1A (0.46) | KDM1AHDAC9MEN1KMT2AAKR1B1 | |
| SCHEMBL4420303 | 0.72 | SIGMAR1 (0.49) | KDM1AMEN1KMT2ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335375-B1 | ANTIHYPERLIPIDEMIC AND ANTIATHEROSCLEROTIC COMPOUNDS AND COMPOSITIONS | WARNER-LAMBERT COMPANY (US) | 1993-06-09 | — | — | EP | claimed |
| EP-0335375-B1 | ANTIHYPERLIPIDEMIC AND ANTIATHEROSCLEROTIC COMPOUNDS AND COMPOSITIONS | WARNER-LAMBERT COMPANY (US) | 1993-06-09 | — | — | EP | disclosed |
| EP-0335375-A2 | Antihyperlipidemic and antiatherosclerotic compounds and compositions | WARNER-LAMBERT COMPANY (US) | 1989-10-04 | — | — | EP | disclosed |