Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KIF11 | P52732 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.40 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.40 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.40 |
| ▸ | MPL | P40238 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9452232 | 0.78 | KDM4E (0.63) | KDM4EMEN1KMT2AKIF11MAPT | |
| SCHEMBL27760770 | 0.77 | MAPT (0.59) | KDM4EMEN1KMT2AKIF11MAPT | |
| SCHEMBL10809192 | 0.76 | KDM4E (0.58) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9500206 | 0.75 | ALDH1A1 (0.49) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9452207 | 0.74 | KDM4E (0.57) | KDM4EMEN1KMT2AKIF11MAPT | |
| SCHEMBL9229419 | 0.73 | KMT2A (0.40) | KDM4EMEN1KMT2AKIF11MAPT | |
| SCHEMBL19032013 | 0.73 | MAPT (0.77) | KDM4EMEN1KMT2AKIF11MAPT | |
| SCHEMBL9499289 | 0.71 | KDM4E (0.37) | KDM4EMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL6824313 | 0.71 | MEN1 (0.56) | KDM4EMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL9178642 | 0.70 | KDM4E (0.63) | KDM4EMEN1KMT2AKIF11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303387-B1 | KYNURENIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS | MERCK SHARP & DOHME LTD. (GB) | 1993-04-21 | — | — | EP | claimed |