Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789026 | 0.79 | RAB9A (0.55) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9502166 | 0.78 | TAS1R3 (0.50) | CYP3A4KMT2AHPGDTAS1R3TAS1R1 | |
| SCHEMBL6138702 | 0.77 | RAB9A (0.56) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL12053329 | 0.76 | CYP3A4 (0.55) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7502509 | 0.75 | RAB9A (0.53) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7332440 | 0.75 | CYP3A4 (0.53) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL17822209 | 0.74 | TAS1R3 (0.69) | RAB9ACYP3A4CYP2C19NPC1CYP1A2 | |
| SCHEMBL30969950 | 0.74 | TAS1R3 (0.69) | RAB9ACYP3A4CYP2C19NPC1CYP1A2 | |
| SCHEMBL17822215 | 0.74 | TAS1R3 (0.69) | RAB9ACYP3A4CYP2C19NPC1CYP1A2 | |
| SCHEMBL24580937 | 0.74 | CYP3A4 (0.52) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375554-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE THREO-DIHYDROXYPHENYLSERINE DERIVATIVES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-05-05 | — | — | EP | disclosed |
| EP-0375554-A2 | Process for producing optically active threo-dihydroxyphenylserine derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-06-27 | — | — | EP | disclosed |