Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.50 |
| ▸ | EDNRA | P25101 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501357 | 0.87 | MME (0.48) | KMT2AHPGDMEN1 | |
| SCHEMBL19625533 | 0.87 | MME (0.48) | KMT2AHPGDMEN1 | |
| SCHEMBL9501146 | 0.81 | NPC1 (0.56) | TAS1R3TAS1R1EDNRACYP3A4 | |
| SCHEMBL10875005 | 0.80 | EDNRA (0.51) | TAS1R3TAS1R1EDNRAKMT2AHPGD | |
| SCHEMBL18076242 | 0.80 | EDNRA (0.51) | TAS1R3TAS1R1EDNRAKMT2AHPGD | |
| SCHEMBL10874124 | 0.80 | EDNRA (0.51) | TAS1R3TAS1R1EDNRAKMT2AHPGD | |
| SCHEMBL805660 | 0.79 | EDNRA (0.55) | TAS1R3TAS1R1EDNRAKMT2AHPGD | |
| Hydrochloric Acid SCHEMBL10874331 | 0.79 | EDNRA (0.50) | TAS1R3TAS1R1EDNRAKMT2AHPGD | |
| SCHEMBL9501476 | 0.78 | RAB9A (0.48) | TAS1R3TAS1R1KMT2AHPGDCYP3A4 | |
| SCHEMBL22404286 | 0.78 | EDNRA (0.56) | TAS1R3TAS1R1EDNRAKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375554-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE THREO-DIHYDROXYPHENYLSERINE DERIVATIVES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-05-05 | — | — | EP | disclosed |
| EP-0375554-A2 | Process for producing optically active threo-dihydroxyphenylserine derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-06-27 | — | — | EP | disclosed |