Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501554 | 1.00 | PAM (0.48) | PAMMTNR1AMTNR1BSMN1; SMN2KDM4E | |
| SCHEMBL8310917 | 0.85 | GPR139 (0.51) | PAMMTNR1AMTNR1BSMN1; SMN2KDM4E | |
| SCHEMBL8310911 | 0.85 | GPR139 (0.51) | PAMMTNR1AMTNR1BSMN1; SMN2KDM4E | |
| SCHEMBL10363720 | 0.80 | PAM (0.52) | PAMMTNR1AMTNR1BSMN1; SMN2KDM4E | |
| SCHEMBL10363718 | 0.80 | PAM (0.52) | PAMMTNR1AMTNR1BSMN1; SMN2KDM4E | |
| SCHEMBL12216271 | 0.78 | POLB (0.54) | PAMSMN1; SMN2MAPTIDO1ALDH1A1 | |
| SCHEMBL15660984 | 0.77 | HDAC3 (0.46) | PAMSMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL18631777 | 0.76 | PAM (0.42) | PAMMTNR1AMTNR1BPPARGPPARD | |
| SCHEMBL16036545 | 0.76 | IDO1 (0.52) | PAMSMN1; SMN2IDO1ALDH1A1POLB | |
| SCHEMBL12216272 | 0.76 | IDO1 (0.52) | PAMSMN1; SMN2IDO1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300849-B1 | PROCESS FOR THE CHEMICAL MODIFICATION OF PROTIDES, AND PRODUCTS SO MODIFIED | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1993-06-16 | — | — | EP | disclosed |
| US-4870016-A | CHANGING SOLUBILITY OF ENZYMES | LEVESQUE GUY (FR) | 1989-09-26 | — | — | US | disclosed |
| EP-0300849-A1 | Process for the chemical modification of protides, and products so modified | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1989-01-25 | — | — | EP | disclosed |