Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.51 |
| ▸ | PAM | P19021 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310917 | 1.00 | GPR139 (0.51) | GPR139PAMKMT2AMAPTALDH1A1 | |
| SCHEMBL10363720 | 0.94 | PAM (0.52) | GPR139PAMKMT2AMAPTALDH1A1 | |
| SCHEMBL10363718 | 0.94 | PAM (0.52) | GPR139PAMKMT2AMAPTALDH1A1 | |
| SCHEMBL16641859 | 0.88 | ALDH1A1 (0.46) | GPR139PAMKMT2AMAPTALDH1A1 | |
| SCHEMBL16641857 | 0.88 | ALDH1A1 (0.46) | GPR139PAMKMT2AMAPTALDH1A1 | |
| SCHEMBL8307911 | 0.87 | TSHR (0.54) | GPR139PAMKMT2AMAPTALDH1A1 | |
| SCHEMBL8307913 | 0.87 | TSHR (0.54) | GPR139PAMKMT2AMAPTALDH1A1 | |
| SCHEMBL10942540 | 0.86 | PTPN1 (0.50) | GPR139IDO1PPARGPPARA | |
| SCHEMBL10805856 | 0.86 | PTPN1 (0.50) | GPR139IDO1PPARGPPARA | |
| SCHEMBL9501547 | 0.85 | PAM (0.48) | GPR139PAMMAPTALDH1A1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116263443-A | Evaluation method for safety influence of benzene series on offshore marine ecological environment | 舟山海关综合技术服务中心 | 2023-06-16 | — | — | CN | disclosed |
| EP-0903346-A1 | SYDNONE IMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-5705527-A | VASODILATORS AND ANGINA PECTORIS | SANKYO COMPANY, LIMITED (JP) | 1998-01-06 | — | — | US | disclosed |
| EP-0641769-B1 | AMINO ACID DERIVATIVE | SANKYO CO (JP) | 1997-01-29 | — | — | EP | disclosed |
| EP-0641769-A1 | AMINO ACID DERIVATIVE | SANKYO COMPANY LIMITED (JP) | 1995-03-08 | — | — | EP | disclosed |