Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | CASP4 | P49662 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP9 | P55211 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2060402 | 0.89 | ACHE (0.45) | PIK3CDPIK3CAPIK3CBPIK3CGCASP1 | |
| SCHEMBL30781048 | 0.82 | PIK3CD (0.47) | PIK3CDPIK3CAPIK3CBPIK3CGCASP1 | |
| SCHEMBL6427738 | 0.82 | PIK3CD (0.47) | PIK3CDPIK3CAPIK3CBPIK3CGCASP1 | |
| SCHEMBL9504216 | 0.81 | PIK3CD (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGCASP1 | |
| SCHEMBL25607649 | 0.80 | CHRM2 (0.51) | PIK3CDPIK3CAPIK3CBPIK3CGCASP1 | |
| SCHEMBL5519599 | 0.78 | ALDH1A1 (0.47) | PIK3CDPIK3CAPIK3CBPIK3CGCASP1 | |
| SCHEMBL25607650 | 0.78 | PIK3CD (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGCASP1 | |
| SCHEMBL10274465 | 0.78 | PIK3CA (0.52) | PIK3CDPIK3CAPIK3CBPIK3CGMEN1 | |
| SCHEMBL7139032 | 0.77 | PIK3CD (0.42) | PIK3CDPIK3CAPIK3CBPIK3CGMEN1 | |
| SCHEMBL9501566 | 0.77 | RAF1 (0.40) | PIK3CAPIK3CBPIK3CGCASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355598-B1 | BETA-PHENOXYETHYL AMINES AND THEIR USE IN THE PREPARATION OF DYES | BAYER AG (DE) | 1993-06-16 | — | — | EP | disclosed |
| US-5126481-A | Cyclization, reduction, decyclization | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-30 | — | — | US | disclosed |
| US-5041629-A | Beta-phenoxyethylamines and their use for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1991-08-20 | — | — | US | disclosed |
| EP-0355598-A2 | Beta-phenoxyethyl amines and their use in the preparation of dyes | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |