SCHEMBL9501602

SCHEMBL9501602

Cc1ccc(-c2cc(C(=O)OC3CCC4CC(C)CCC4C3)c(N)c3c2C(=O)c2ccccc2C3=S)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
HPGD P15428 1/20 0.33
HCRTR1 O43613 4/20 0.32
HCRTR2 O43614 4/20 0.32
LMNA P02545 1/20 0.32
CYP3A4 P08684 1/20 0.32
SCN1A P35498 1/20 0.32
SCN2A Q99250 1/20 0.32
SCN3A Q9NY46 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
RAB9A P51151 1/20 0.31
KDM4E B2RXH2 2/20 0.31
MAPK1 P28482 2/20 0.31
RAD52 P43351 1/20 0.31
GRK6 P43250 1/20 0.30
MEN1 O00255 1/20 0.30
USP2 O75604 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9503045 0.92 HCRTR1 (0.33) ALDH1A1HCRTR1HCRTR2SCN1ASCN2A
SCHEMBL10580668 0.92 ALDH1A1 (0.33) ALDH1A1HPGDLMNACYP3A4SCN1A
SCHEMBL9503099 0.92 SCN1A (0.32) ALDH1A1HCRTR1HCRTR2SCN1ASCN2A
SCHEMBL9505273 0.86 SCN1A (0.37) ALDH1A1LMNASCN1ASCN2ASCN3A
SCHEMBL9501621 0.81 MEN1 (0.49) ALDH1A1HPGDLMNACYP3A4SCN1A
SCHEMBL9501616 0.81 MEN1 (0.49) ALDH1A1HPGDLMNACYP3A4SCN1A
SCHEMBL9503042 0.81 HTR3E (0.36) HCRTR1HCRTR2LMNARAB9A
SCHEMBL9502281 0.81 P2RY2 (0.49)
SCHEMBL9501597 0.81 ADORA2A (0.41) ALDH1A1HPGDLMNARAB9AKDM4E
SCHEMBL9501664 0.79 SCN1A (0.33) ALDH1A1HPGDLMNASCN1ASCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0307866-B1 DICHROIC COLORING AGENTS FOR LIQUID CRYSTAL DISPLAYS MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-05-12 EP disclosed
US-4883611-A ANTHRAQUINONE COMPOUND CONTAINING DECAHYDRONAPHTHYL GROUP MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1989-11-28 US disclosed
EP-0307866-A2 Dichroic coloring agents for liquid crystal displays MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-03-22 EP disclosed