Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637438 | 1.00 | CTSL (0.57) | CTSLCTSBMAPTALDH1A1SIRT6 | |
| SCHEMBL27789 | 0.91 | MAPT (0.64) | MAPTALDH1A1SIRT6POLBADRB1 | |
| SCHEMBL25205345 | 0.88 | CTSL (0.78) | CTSLCTSBMAPTALDH1A1MEN1 | |
| SCHEMBL25218086 | 0.88 | CTSL (0.78) | CTSLCTSBMAPTALDH1A1MEN1 | |
| SCHEMBL6218863 | 0.85 | MAPT (0.66) | CTSLCTSBMAPTALDH1A1SIRT6 | |
| SCHEMBL9651198 | 0.83 | MAPT (0.77) | CTSLCTSBMAPTALDH1A1SIRT6 | |
| SCHEMBL8724462 | 0.82 | CTSL (0.53) | CTSLCTSBMAPTALDH1A1SIRT6 | |
| SCHEMBL8724463 | 0.82 | CTSL (0.53) | CTSLCTSBMAPTALDH1A1SIRT6 | |
| SCHEMBL9649952 | 0.82 | MAPT (0.81) | CTSLCTSBMAPTALDH1A1SIRT6 | |
| SCHEMBL854301 | 0.82 | MAPT (0.56) | MAPTALDH1A1SIRT6POLBADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316662-B1 | ACRYLIC COPOLYMERS EXHIBITING NONLINEAR OPTICAL RESPONSE | HOECHST CELANESE CORPORATION (US) | 1993-05-12 | — | — | EP | disclosed |
| EP-0290061-B1 | LINEAR ADDITION POLYMER WITH HYPERPOLARIZABLE SIDE GROUPS | Akzo Nobel N.V. (NL) | 1992-07-15 | — | — | EP | disclosed |
| US-5043391-A | Linear addition polymer with hyperpolarizable side groups | AKZO N.V. (NL) | 1991-08-27 | — | — | US | disclosed |
| US-4999401-A | Electro-optical Laminates | AKZO N.V. (NL) | 1991-03-12 | — | — | US | disclosed |
| US-4913845-A | Organic-inorganic composites with enhanced nonlinear optical response | HOECHST CELANESE CORP. (US) | 1990-04-03 | — | — | US | disclosed |
| EP-0334176-A1 | Organic-inorganic composites with enhanced nonlinear optical response | HOECHST CELANESE CORPORATION (US) | 1989-09-27 | — | — | EP | disclosed |
| US-4867516-A | Electro-optically induced optical waveguide, and active devices comprising such a waveguide | STAAT DER NEDERLANDEN (NL) | 1989-09-19 | — | — | US | disclosed |
| EP-0316662-A1 | Acrylic copolymers exhibiting nonlinear optical response | HOECHST CELANESE CORPORATION (US) | 1989-05-24 | — | — | EP | disclosed |
| US-4828758-A | COLLOIDAL METAL IN POLYMER MATRIX | Hoechst Gelanese Corp. (US) | 1989-05-09 | — | — | US | disclosed |
| US-4801670-A | Acrylic copolymers exhibiting nonlinear optical response | HOECAST CELANESE CORP. (US) | 1989-01-31 | — | — | US | disclosed |