Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.81 |
| ▸ | CTSL | P07711 | 1/20 | 0.71 |
| ▸ | CTSB | P07858 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.51 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9651198 | 0.98 | MAPT (0.77) | MAPTCTSLCTSBLMNAALDH1A1 | |
| SCHEMBL6607374 | 0.90 | MAPT (1.00) | MAPTCTSLCTSBLMNAALDH1A1 | |
| SCHEMBL85552 | 0.90 | MAPT (1.00) | MAPTCTSLCTSBLMNAALDH1A1 | |
| SCHEMBL223626 | 0.90 | MAPT (1.00) | MAPTCTSLCTSBLMNAALDH1A1 | |
| SCHEMBL378458 | 0.88 | MAPT (0.96) | MAPTCTSLCTSBLMNAALDH1A1 | |
| SCHEMBL9647832 | 0.86 | MITF (0.70) | MAPTCTSLCTSBALDH1A1SIRT6 | |
| SCHEMBL4940911 | 0.85 | MAPT (0.58) | MAPTCTSLCTSBLMNAALDH1A1 | |
| SCHEMBL1851861 | 0.84 | MAPT (0.89) | MAPTCTSLCTSBLMNAALDH1A1 | |
| SCHEMBL7048817 | 0.83 | MAPT (0.85) | MAPTCTSLCTSBLMNAALDH1A1 | |
| SCHEMBL7718270 | 0.82 | ALDH1A1 (0.69) | MAPTCTSLCTSBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313475-B1 | AN OPTICAL ARTICLE CONTAINING A TRANSMISSION MEDIUM EXHIBITING A HIGH LEVEL OF SECOND ORDER POLARIZATION SUSCEPTIBILITY | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1992-12-23 | — | — | EP | disclosed |
| US-4886339-A | MOLECULAR DIPOLES HELD IN POLAR ALIGNMENT BY A CROSSLINKED POLYMERIC BINDER; STABILITY | EASTMAN KODAK COMPANY (US) | 1989-12-12 | — | — | US | disclosed |
| EP-0313475-A2 | An optical article containing a transmission medium exhibiting a high level of second order polarization susceptibility | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-04-26 | — | — | EP | disclosed |