Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | USP18 | Q9UMW8 | 1/20 | 0.44 |
| ▸ | UCHL5 | Q9Y5K5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8724462 | 1.00 | CTSL (0.53) | CTSLCTSBPTGS2PTGS1MAPT | |
| SCHEMBL6710563 | 0.91 | MAPT (0.58) | MAPTSIRT6ALDH1A1POLBADRB1 | |
| Hydrochloric Acid SCHEMBL6707092 | 0.89 | MAPT (0.56) | MAPTSIRT6ALDH1A1POLBADRB1 | |
| SCHEMBL9501629 | 0.82 | CTSL (0.57) | CTSLCTSBMAPTSIRT6ALDH1A1 | |
| SCHEMBL9637438 | 0.82 | CTSL (0.57) | CTSLCTSBMAPTSIRT6ALDH1A1 | |
| SCHEMBL3549925 | 0.80 | MAPT (0.58) | MAPTSIRT6ALDH1A1POLBADRB1 | |
| SCHEMBL30135452 | 0.80 | SIRT6 (0.51) | MAPTSIRT6ALDH1A1POLBADRB1 | |
| SCHEMBL9651198 | 0.80 | MAPT (0.77) | CTSLCTSBPTGS2MAPTNPC1 | |
| SCHEMBL9649952 | 0.78 | MAPT (0.81) | CTSLCTSBPTGS2MAPTNPC1 | |
| SCHEMBL9647832 | 0.77 | MITF (0.70) | CTSLCTSBMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0868682-A1 | ELECTRO- OR OPTO-OPTICAL DEVICE STABLE IN THE 600-1600 NANOMETER WAVELENGTH RANGE | Akzo Nobel N.V. (NL) | 1998-10-07 | — | — | EP | disclosed |
| US-5776375-A | CONTAINING NONLINEAR OPTICALLY ACTIVE POLYMER | AKZO NOBEL N.V. (NL) | 1998-07-07 | — | — | US | disclosed |
| WO-1997023807-A1 | ELECTRO- OR OPTO-OPTICAL DEVICE STABLE IN THE 600-1600 NANOMETER WAVELENGTH RANGE | AKZO NOBEL N.V. (NL) | 1997-07-03 | — | — | WO | disclosed |
| EP-0780722-A1 | Electro-optical device stable in the 600-1600 nanometer wavelength range | Akzo Nobel N.V. (NL) | 1997-06-25 | — | — | EP | disclosed |