Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795228 | 1.00 | SMN1; SMN2 (0.34) | SMN1; SMN2ALDH1A1HPGDL3MBTL1SMYD3 | |
| SCHEMBL9498710 | 1.00 | SMN1; SMN2 (0.34) | SMN1; SMN2ALDH1A1HPGDL3MBTL1SMYD3 | |
| SCHEMBL9795077 | 0.86 | L3MBTL1 (0.35) | SMN1; SMN2ALDH1A1L3MBTL1KMT2ATMEM97 | |
| SCHEMBL9499509 | 0.82 | SMYD3 (0.42) | SMN1; SMN2ALDH1A1L3MBTL1SMYD3 | |
| SCHEMBL9795275 | 0.82 | SMYD3 (0.42) | SMN1; SMN2ALDH1A1L3MBTL1SMYD3 | |
| SCHEMBL9499579 | 0.82 | SMYD3 (0.42) | SMN1; SMN2ALDH1A1L3MBTL1SMYD3 | |
| SCHEMBL9498706 | 0.81 | SMYD3 (0.37) | SMN1; SMN2ALDH1A1HPGDL3MBTL1SMYD3 | |
| SCHEMBL9501486 | 0.81 | SMYD3 (0.37) | SMN1; SMN2ALDH1A1HPGDL3MBTL1SMYD3 | |
| SCHEMBL9795170 | 0.81 | SMYD3 (0.37) | SMN1; SMN2ALDH1A1HPGDL3MBTL1SMYD3 | |
| SCHEMBL16741512 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1HPGDSMYD3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367019-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING NITROXYALKYL AMINE WITH AN AMIDE FUNCTION, AND METHOD FOR THE PREPARATION OF THE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1993-05-12 | — | — | EP | disclosed |