Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 18/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499509 | 1.00 | SMYD3 (0.42) | SMYD3ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9795275 | 1.00 | SMYD3 (0.42) | SMYD3ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9795380 | 0.88 | ALDH1A1 (0.38) | SMYD3ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9498710 | 0.82 | SMN1; SMN2 (0.34) | SMYD3ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9501636 | 0.82 | SMN1; SMN2 (0.34) | SMYD3ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9795228 | 0.82 | SMN1; SMN2 (0.34) | SMYD3ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9795372 | 0.80 | HSD11B1 (0.37) | SMYD3ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9497980 | 0.79 | SMYD3 (0.44) | SMYD3ALDH1A1L3MBTL1 | |
| SCHEMBL9497857 | 0.79 | SMYD3 (0.44) | SMYD3ALDH1A1L3MBTL1 | |
| SCHEMBL9795527 | 0.79 | SMYD3 (0.44) | SMYD3ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367019-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING NITROXYALKYL AMINE WITH AN AMIDE FUNCTION, AND METHOD FOR THE PREPARATION OF THE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1993-05-12 | — | — | EP | disclosed |
| EP-0367019-A1 | Pharmaceutical compositions containing nitroxyalkyl amine with an amide function, and method for the preparation of the compounds | Roche Diagnostics GmbH (DE) | 1990-05-09 | — | — | EP | disclosed |