Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501486 | 1.00 | SMYD3 (0.37) | SMYD3SMN1; SMN2ALDH1A1L3MBTL1BCHE | |
| SCHEMBL9498706 | 1.00 | SMYD3 (0.37) | SMYD3SMN1; SMN2ALDH1A1L3MBTL1BCHE | |
| Fumaric Acid SCHEMBL9795108 | 0.93 | POLB (0.37) | SMYD3SMN1; SMN2ALDH1A1L3MBTL1BCHE | |
| SCHEMBL9137074 | 0.86 | SMYD3 (0.37) | SMYD3SMN1; SMN2ALDH1A1L3MBTL1BCHE | |
| SCHEMBL9795290 | 0.86 | ALDH1A1 (0.37) | SMYD3SMN1; SMN2ALDH1A1L3MBTL1BCHE | |
| SCHEMBL16741512 | 0.82 | SMN1; SMN2 (0.50) | SMYD3SMN1; SMN2ALDH1A1HDAC3HDAC1 | |
| SCHEMBL9497980 | 0.81 | SMYD3 (0.44) | SMYD3ALDH1A1L3MBTL1 | |
| SCHEMBL9795527 | 0.81 | SMYD3 (0.44) | SMYD3ALDH1A1L3MBTL1 | |
| SCHEMBL9497857 | 0.81 | SMYD3 (0.44) | SMYD3ALDH1A1L3MBTL1 | |
| SCHEMBL9501636 | 0.81 | SMN1; SMN2 (0.34) | SMYD3SMN1; SMN2ALDH1A1L3MBTL1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |