SCHEMBL9501638

SCHEMBL9501638

CC(CCO[N+](=O)[O-])NC(=O)C(C)(C)N

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.31
PTGS1 P23219 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fumaric Acid SCHEMBL9795237 0.92 ALDH1A1 (0.31)
SCHEMBL4593304 0.76 PTGS2 (0.33) PTGS2PTGS1
SCHEMBL9497759 0.76 POLB (0.34) PTGS2PTGS1
SCHEMBL9497848 0.74 MEN1 (0.40) PTGS2PTGS1
SCHEMBL9497710 0.73 KDM4E (0.30)
SCHEMBL9501618 0.72 KDM4E (0.37) PTGS2PTGS1
SCHEMBL10157900 0.69 ALDH1A1 (0.33) PTGS2PTGS1
SCHEMBL9499920 0.68 ALDH1A1 (0.41)
Fumaric Acid SCHEMBL9795052 0.68 MEN1 (0.36)
SCHEMBL18243623 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0367019-B1 PHARMACEUTICAL COMPOSITIONS CONTAINING NITROXYALKYL AMINE WITH AN AMIDE FUNCTION, AND METHOD FOR THE PREPARATION OF THE COMPOUNDS Roche Diagnostics GmbH (DE) 1993-05-12 EP disclosed
EP-0367019-A1 Pharmaceutical compositions containing nitroxyalkyl amine with an amide function, and method for the preparation of the compounds Roche Diagnostics GmbH (DE) 1990-05-09 EP disclosed