Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2803445 | 0.78 | KCNH2 (0.38) | — | |
| SCHEMBL2803442 | 0.77 | ATM (0.31) | — | |
| Hydrochloric Acid SCHEMBL11817782 | 0.71 | DPP4 (0.37) | — | |
| SCHEMBL23111866 | 0.67 | CA12 (0.33) | — | |
| SCHEMBL9498099 | 0.67 | LMNA (0.38) | — | |
| SCHEMBL5072598 | 0.66 | ALDH1A1 (0.34) | — | |
| SCHEMBL9497848 | 0.66 | MEN1 (0.40) | MAPT | |
| SCHEMBL16926131 | 0.66 | KCNH2 (0.36) | — | |
| SCHEMBL10444401 | 0.66 | — | — | |
| SCHEMBL7105554 | 0.66 | ZDHHC20 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367019-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING NITROXYALKYL AMINE WITH AN AMIDE FUNCTION, AND METHOD FOR THE PREPARATION OF THE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1993-05-12 | — | — | EP | disclosed |
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |
| EP-0367019-A1 | Pharmaceutical compositions containing nitroxyalkyl amine with an amide function, and method for the preparation of the compounds | Roche Diagnostics GmbH (DE) | 1990-05-09 | — | — | EP | disclosed |