Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807071 | 0.83 | USP2 (0.45) | MAPK1PTGDR2MAPTKDM4ECA2 | |
| SCHEMBL7090155 | 0.82 | CYP2C19 (0.61) | MAPK1NPSR1CYP2C19MAPTKDM4E | |
| SCHEMBL27170735 | 0.80 | KDM4E (0.45) | MAPK1NPSR1CYP2C19PTGDR2MAPT | |
| SCHEMBL75920 | 0.80 | MAPK1 (0.59) | MAPK1NPSR1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6671333 | 0.79 | ALDH1A1 (0.47) | MAPK1NPSR1CYP2C19PTGDR2MAPT | |
| SCHEMBL10651246 | 0.77 | KDM4E (0.42) | MAPK1NPSR1CYP2C19PTGDR2MAPT | |
| SCHEMBL6549878 | 0.77 | CA1 (0.42) | MAPK1NPSR1CYP2C19PTGDR2MAPT | |
| SCHEMBL5807025 | 0.77 | ALDH1A1 (0.53) | MAPK1NPSR1CYP2C19MAPTKDM4E | |
| SCHEMBL9502507 | 0.77 | KDM4E (0.39) | KDM4ESMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL958236 | 0.76 | EGFR (0.48) | MAPK1NPSR1CYP2C19PTGDR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324917-B1 | LOW PLATE-OUT POLYCARBONATES | GENERAL ELECTRIC COMPANY (US) | 1993-06-30 | — | — | EP | claimed |
| EP-0324917-A1 | Low plate-out polycarbonates | GENERAL ELECTRIC COMPANY (US) | 1989-07-26 | — | — | EP | claimed |
| US-4841015-A | Low plate-out polycarbonate end capped with phenoxy acetic acid | GENERAL ELECTRIC COMPANY (US) | 1989-06-20 | — | — | US | claimed |