Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ARG1 | P05089 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9497914 | 1.00 | L3MBTL1 (0.40) | L3MBTL1ARG1TDP1KMT2AHDAC8 | |
| SCHEMBL9019503 | 0.82 | TDP1 (0.40) | L3MBTL1TDP1ATG4BALDH1A1BCHE | |
| SCHEMBL28655000 | 0.82 | TDP1 (0.54) | ARG1TDP1KMT2ATSHRALDH1A1 | |
| SCHEMBL8239366 | 0.82 | TDP1 (0.54) | ARG1TDP1KMT2ATSHRALDH1A1 | |
| SCHEMBL28654997 | 0.82 | TDP1 (0.54) | ARG1TDP1KMT2ATSHRALDH1A1 | |
| SCHEMBL9795326 | 0.81 | TDP1 (0.61) | L3MBTL1TDP1ATG4BALDH1A1BCHE | |
| SCHEMBL9795492 | 0.81 | L3MBTL1 (0.34) | L3MBTL1TDP1 | |
| SCHEMBL9795460 | 0.78 | TDP1 (0.41) | ARG1TDP1ATG4BALDH1A1BCHE | |
| SCHEMBL9497748 | 0.78 | SMYD3 (0.39) | ARG1KMT2ABCHE | |
| SCHEMBL9795289 | 0.78 | SMYD3 (0.39) | ARG1KMT2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367019-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING NITROXYALKYL AMINE WITH AN AMIDE FUNCTION, AND METHOD FOR THE PREPARATION OF THE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1993-05-12 | — | — | EP | disclosed |
| EP-0367019-A1 | Pharmaceutical compositions containing nitroxyalkyl amine with an amide function, and method for the preparation of the compounds | Roche Diagnostics GmbH (DE) | 1990-05-09 | — | — | EP | disclosed |