SCHEMBL950180

SCHEMBL950180

O=C(O)c1ccnn1-c1ncccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 3/20 0.41
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MYC P01106 1/20 0.39
TRPA1 O75762 2/20 0.39
PKM P14618 1/20 0.38
KDM4E B2RXH2 2/20 0.36
KDM6B O15054 1/20 0.36
KDM6A O15550 1/20 0.36
TET3 O43151 1/20 0.36
KDM4A O75164 1/20 0.36
KDM4B O94953 1/20 0.36
KDM5C P41229 1/20 0.36
KDM4D Q6B0I6 1/20 0.36
TET2 Q6N021 1/20 0.36
ALKBH5 Q6P6C2 1/20 0.36
TET1 Q8NFU7 1/20 0.36
FTO Q9C0B1 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
KDM4C Q9H3R0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28061610 0.88 MALT1 (0.39) MALT1TRPA1CYP17A1CYP1A2
SCHEMBL2427927 0.86 SMN1; SMN2 (0.40) MALT1LMNASMN1; SMN2TRPA1CYP17A1
SCHEMBL27899576 0.82 F2 (0.46) MALT1TRPA1KDM4EL3MBTL1CYP1A2
SCHEMBL12911853 0.81 MYC (0.45) LMNASMN1; SMN2MYCKDM4EKDM6B
SCHEMBL29185083 0.79 PDE4B (0.43) LMNAKDM4EL3MBTL1KMT2ATDP1
SCHEMBL27914601 0.79 MALT1 (0.32) MALT1TRPA1CYP17A1CYP1A2
SCHEMBL4543706 0.79 KDM4C (0.38) LMNASMN1; SMN2KDM4CL3MBTL1MEN1
SCHEMBL958268 0.79 MALT1 (0.40) MALT1LMNASMN1; SMN2MYCTRPA1
SCHEMBL384656 0.79 KMT2A (0.43) MALT1LMNASMN1; SMN2KDM4EL3MBTL1
SCHEMBL29558300 0.79 MALT1 (0.40) MALT1LMNASMN1; SMN2MYCTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115738907-B 3-bromo-1- (3-chloro-2-pyridyl) -1H-pyrazole-5-formic acid production system and process thereof 安徽中山化工有限公司 2023-09-01 CN claimed
EP-4387449-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR Syngenta Crop Protection AG (CH) 2024-06-26 EP disclosed
CN-118076228-A Methods for controlling diamide-resistant pests and compounds thereof 先正达农作物保护股份公司 2024-05-24 CN disclosed
CN-117813006-A Methods for controlling diamide-resistant pests and compounds thereof 先正达农作物保护股份公司 2024-04-02 CN disclosed
CN-117715523-A Methods for controlling diamide-resistant pests and compounds thereof 先正达农作物保护股份公司 2024-03-15 CN disclosed
EP-4232442-A1 A PROCESS FOR THE PREPARATION OF CHLORANTRANILIPROLE Gharda Chemicals Limited (IN) 2023-08-30 EP disclosed
WO-2023021020-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-02-23 WO disclosed
WO-2022084887-A1 A PROCESS FOR THE PREPARATION OF CHLORANTRANILIPROLE GHARDA CHEMICALS LIMITED (IN) 2022-04-28 WO disclosed
EP-3976596-A1 METHODS FOR THE PREPARATION OF ETHYL 3-BROMO-1-(3-CHLOROPYRIDIN-2-YL)-1H-PYRAZOLE-5-CARBOXYLATE FMC Corporation (US) 2022-04-06 EP disclosed
CN-114011370-A Equipment for efficiently producing pyrazolecarboxylic acid and improvement method thereof 江苏优普生物化学科技股份有限公司 2022-02-08 CN disclosed
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-16 US disclosed
WO-2009027393-A2 PYRAZOLE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS BASF SE (DE) 2009-03-05 WO disclosed
CN-100441576-C Cyano anthranilamide insecticides DU PONT (US) 2008-12-10 CN disclosed
CN-101287721-A Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL CO (JP) 2008-10-15 CN disclosed
EP-1937664-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2008-07-02 EP disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 WO disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed
CN-1829707-A Cyano anthranilamide insecticides DU PONT (US) 2006-09-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same ACHE, DDT, CAT MALT1 4865/4885LMNA 4343/4885SMN1; SMN2 2755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.