Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 6/20 | 0.41 |
| ▸ | BID | P55957 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 5/20 | 0.38 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504617 | 0.85 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1MAPTRXFP1DAGLA | |
| SCHEMBL9502587 | 0.83 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1MAPTRXFP1DAGLA | |
| SCHEMBL9505492 | 0.80 | NPC1 (0.44) | CYSLTR2CYSLTR1DAGLABIDBCL2L1 | |
| SCHEMBL9505459 | 0.77 | CYSLTR2 (0.71) | CYSLTR2CYSLTR1MAPTRXFP1DAGLA | |
| SCHEMBL9505512 | 0.76 | CYSLTR2 (0.70) | CYSLTR2CYSLTR1MAPTRXFP1TBXAS1 | |
| SCHEMBL9505544 | 0.73 | MAPT (0.40) | CYSLTR2CYSLTR1MAPT | |
| SCHEMBL9503341 | 0.73 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1MAPTRXFP1DAGLA | |
| SCHEMBL9501467 | 0.71 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1DAGLACES1FAAH | |
| SCHEMBL9503345 | 0.71 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1MAPTRXFP1DAGLA | |
| SCHEMBL9301491 | 0.71 | CYSLTR2 (0.78) | CYSLTR2CYSLTR1MAPTRXFP1BID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548291-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992005156-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-04-02 | — | — | WO | disclosed |