SCHEMBL9501833

SCHEMBL9501833

O=C(O)c1ccccc1Nc1ccc(Oc2ccccc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.68
MEN1 O00255 2/20 0.68
KMT2A Q03164 2/20 0.68
ALDH1A1 P00352 1/20 0.68
TEAD4 Q15561 1/20 0.68
FABP4 P15090 2/20 0.67
AKR1C3 P42330 3/20 0.60
AKR1C2 P52895 3/20 0.60
PTGS1 P23219 1/20 0.60
SIRT2 Q8IXJ6 2/20 0.58
SIRT1 Q96EB6 1/20 0.58
TAS2R14 Q9NYV8 1/20 0.57
CTSV O60911 1/20 0.55
CTSL P07711 1/20 0.55
MAPK8 P45983 1/20 0.55
ALOX15 P16050 1/20 0.54
PNLIP P16233 1/20 0.53
TTR P02766 1/20 0.53
RECQL P46063 1/20 0.51
BLM P54132 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6475426 0.91 MEN1 (0.64) MAPTMEN1KMT2AALDH1A1TEAD4
SCHEMBL18109767 0.88 FABP4 (0.85) MAPTMEN1KMT2AALDH1A1TEAD4
SCHEMBL355486 0.85 AKR1C3 (0.72) MAPTMEN1KMT2AALDH1A1TEAD4
SCHEMBL30213377 0.85 AKR1C3 (0.72) MAPTMEN1KMT2AALDH1A1TEAD4
SCHEMBL7841736 0.84 FABP4 (0.85) MAPTMEN1KMT2AALDH1A1TEAD4
SCHEMBL4225339 0.84 AKR1C3 (0.73) MAPTFABP4AKR1C3AKR1C2SIRT2
Fenamic Acid SCHEMBL29622832 0.84 FABP4 (0.92) MAPTMEN1KMT2AALDH1A1TEAD4
Fenamic Acid SCHEMBL25828 0.84 FABP4 (0.92) MAPTMEN1KMT2AALDH1A1TEAD4
SCHEMBL15943631 0.82 SIRT2 (0.58) MAPTMEN1KMT2AALDH1A1TEAD4
SCHEMBL22650202 0.82 MEN1 (0.73) MAPTMEN1KMT2AFABP4AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0253276-B1 PIGMENTS OF THE QUINACRIDONEQUINONE GROUP, THEIR PREPARATION PROCESS AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1993-04-21 EP disclosed
US-4881980-A ACRIDONES INCORPORATED IN CRYSTAL LATTICE HOECHST AKTIENGESELLSCHAFT (DE) 1989-11-21 US disclosed
EP-0253276-A2 Pigments of the quinacridonequinone group, their preparation process and their use HOECHST AKTIENGESELLSCHAFT (DE) 1988-01-20 EP disclosed