Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 3/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9586361 | 0.88 | GRM5 (0.42) | IRAK4GRM5TGFBR1CCR1CCR8 | |
| SCHEMBL4333513 | 0.78 | HTT (0.50) | GRM5CCR1CCR8SLC6A2SLC6A4 | |
| SCHEMBL15470589 | 0.76 | CCR1 (0.60) | GRM5TGFBR1CCR1CCR8IDH1 | |
| SCHEMBL8854902 | 0.75 | MEN1 (0.55) | GRM5TGFBR1CCR1CCR8 | |
| SCHEMBL6559740 | 0.74 | KMT2A (0.41) | SLC6A2SLC6A4SLC6A3PIM1PIM2 | |
| SCHEMBL9500899 | 0.72 | BRD4 (0.41) | GRM5TGFBR1CCR1CCR8POLB | |
| SCHEMBL7964553 | 0.71 | KDM4E (0.59) | GRM5CCR1CCR8HTTPOLB | |
| SCHEMBL9026653 | 0.70 | CCR1 (0.42) | GRM5TGFBR1CCR1CCR8MAPK14 | |
| SCHEMBL10539132 | 0.69 | CYP2A6 (0.53) | GRM5TGFBR1CCR1CCR8MAPK14 | |
| SCHEMBL9031119 | 0.69 | GRM4 (0.62) | GRM5TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185339-A | FUNGICIDAL COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0459662-A1 | Fungicidal compounds | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |