Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918097 | 0.85 | HTR1F (0.50) | KMT2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL8824695 | 0.79 | ALDH1A1 (0.55) | KMT2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9303219 | 0.77 | ALDH1A1 (0.56) | KMT2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9502616 | 0.77 | CYP19A1 (0.60) | KMT2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL4505291 | 0.76 | KMT2A (0.53) | KMT2AALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL8889074 | 0.76 | KMT2A (0.80) | KMT2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL4504471 | 0.75 | TSHR (0.52) | KMT2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9624375 | 0.74 | KMT2A (0.67) | KMT2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL220059 | 0.74 | KMT2A (0.72) | KMT2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9716625 | 0.73 | KDM4E (0.44) | KMT2AALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317332-B1 | SULFONANILIDE COMPOUNDS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-4885367-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS; SIDE EFFECT REDUCTION | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1989-12-05 | — | — | US | disclosed |
| EP-0317332-A2 | Sulfonanilide compounds | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1989-05-24 | — | — | EP | disclosed |