Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | BLM | P54132 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | NSD2 | O96028 | 3/20 | 0.63 |
| ▸ | USP2 | O75604 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | TOP2A | P11388 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | MTOR | P42345 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.63 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.63 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.63 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.63 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9502052 | 0.99 | RECQL (0.64) | RECQLMAPK1TDP1MEN1BLM | |
| SCHEMBL9679834 | 0.88 | MEN1 (0.49) | RECQLMAPK1TDP1MEN1BLM | |
| Hydrochloric Acid SCHEMBL9680102 | 0.87 | MEN1 (0.50) | RECQLMAPK1TDP1MEN1BLM | |
| Hydrochloric Acid SCHEMBL9501080 | 0.87 | KMT2A (0.73) | RECQLMAPK1TDP1MEN1BLM | |
| Mitoxantrone SCHEMBL3463074 | 0.86 | MEN1 (0.82) | RECQLMAPK1TDP1MEN1BLM | |
| SCHEMBL10976132 | 0.84 | MEN1 (0.69) | RECQLMAPK1TDP1MEN1BLM | |
| SCHEMBL9504757 | 0.83 | TOP2B (0.60) | RECQLMAPK1TDP1MEN1BLM | |
| SCHEMBL10633317 | 0.82 | MEN1 (0.75) | RECQLMAPK1TDP1MEN1BLM | |
| SCHEMBL11275434 | 0.79 | MEN1 (0.75) | RECQLMAPK1TDP1MEN1BLM | |
| SCHEMBL11041318 | 0.79 | MEN1 (0.75) | RECQLMAPK1TDP1MEN1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320960-B1 | AMINO ANTHRACENEDIONES-BIS PLATINUM COMPLEXES, USEFUL AS ANTITUMORAL AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-05-12 | — | — | EP | disclosed |
| EP-0396588-A1 | AMINO ANTHRACENEDIONES-BIS PLATINUM COMPLEXES, USEFUL AS ANTITUMORAL AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1990-11-14 | — | — | EP | disclosed |
| WO-1989005815-A1 | AMINO ANTHRACENEDIONES-BIS PLATINUM COMPLEXES, USEFUL AS ANTITUMORAL AGENTS | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-06-29 | — | — | WO | disclosed |
| EP-0320960-A1 | Amino anthracenediones-bis platinum complexes, useful as antitumoral agents | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1989-06-21 | — | — | EP | disclosed |