Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2B | Q02880 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | BLM | P54132 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | NSD2 | O96028 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MTOR | P42345 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503729 | 0.91 | TOP2B (0.50) | TOP2BMEN1BLMKMT2ANSD2 | |
| SCHEMBL16343810 | 0.89 | MEN1 (0.55) | TOP2BMEN1BLMKMT2ANSD2 | |
| Hydrochloric Acid SCHEMBL9502000 | 0.86 | TOP2B (0.71) | TOP2BMEN1BLMKMT2ANSD2 | |
| SCHEMBL16343655 | 0.83 | MAPT (0.63) | TOP2BMEN1BLMKMT2ANSD2 | |
| SCHEMBL9501985 | 0.83 | RECQL (0.63) | TOP2BMEN1BLMKMT2ANSD2 | |
| SCHEMBL9679834 | 0.82 | MEN1 (0.49) | TOP2BMEN1BLMKMT2ANSD2 | |
| Hydrochloric Acid SCHEMBL9502052 | 0.82 | RECQL (0.64) | TOP2BMEN1BLMKMT2ANSD2 | |
| SCHEMBL16343445 | 0.82 | MEN1 (0.54) | TOP2BMEN1BLMKMT2ANSD2 | |
| Hydrochloric Acid SCHEMBL9680102 | 0.81 | MEN1 (0.50) | TOP2BMEN1BLMKMT2ANSD2 | |
| SCHEMBL22715848 | 0.81 | MEN1 (0.52) | TOP2BMEN1BLMKMT2ANSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320960-B1 | AMINO ANTHRACENEDIONES-BIS PLATINUM COMPLEXES, USEFUL AS ANTITUMORAL AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-05-12 | — | — | EP | disclosed |
| US-5145848-A | AMINO ANTHRACENEDIONES-BIS PLATINUM COMPLEXES, USEFUL AS ANTITUMORAL AGENTS | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1992-09-08 | — | — | US | disclosed |
| EP-0320960-A1 | Amino anthracenediones-bis platinum complexes, useful as antitumoral agents | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1989-06-21 | — | — | EP | disclosed |