Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.60 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL947597 | 0.82 | S1PR1 (0.55) | S1PR1S1PR5S1PR4 | |
| SCHEMBL948110 | 0.81 | S1PR1 (0.59) | S1PR1S1PR5S1PR4 | |
| SCHEMBL947736 | 0.80 | SLC6A4 (0.42) | — | |
| Trifluoroacetic Acid SCHEMBL948308 | 0.78 | S1PR1 (0.80) | S1PR1S1PR5S1PR4 | |
| SCHEMBL944763 | 0.78 | TRPV1 (0.50) | — | |
| SCHEMBL1918221 | 0.76 | S1PR1 (0.83) | S1PR1S1PR5S1PR4CYP2C9 | |
| SCHEMBL1918217 | 0.76 | S1PR1 (0.83) | S1PR1S1PR5S1PR4CYP2C9 | |
| SCHEMBL30534223 | 0.76 | S1PR1 (0.83) | S1PR1S1PR5S1PR4CYP2C9 | |
| SCHEMBL30534220 | 0.76 | S1PR1 (0.83) | S1PR1S1PR5S1PR4CYP2C9 | |
| SCHEMBL30534221 | 0.76 | S1PR1 (0.83) | S1PR1S1PR5S1PR4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011005295-A1 | MODULATORS OF THE SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2011-01-13 | — | — | WO | disclosed |