Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 10/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL508302 | 0.84 | GABRA1 (0.53) | GABRA1GABRB2MEN1KMT2AMAPT | |
| SCHEMBL30365997 | 0.80 | GABRA1 (0.59) | GABRA1GABRB2MEN1KMT2AMAPT | |
| SCHEMBL40309 | 0.80 | GABRA1 (0.59) | GABRA1GABRB2MEN1KMT2AMAPT | |
| SCHEMBL2237166 | 0.79 | GABRA1 (0.54) | GABRA1GABRB2MEN1KMT2AMAPT | |
| SCHEMBL9615189 | 0.79 | GABRA1 (0.58) | GABRA1GABRB2MEN1KMT2AMAPT | |
| SCHEMBL5491894 | 0.78 | BCAT2 (0.55) | GABRA1GABRB2MEN1KMT2AMAPT | |
| SCHEMBL680147 | 0.78 | GABRA1 (0.61) | GABRA1GABRB2MEN1KMT2AMAPT | |
| SCHEMBL29889296 | 0.77 | GABRA1 (0.56) | GABRA1GABRB2MEN1KMT2AMAPT | |
| SCHEMBL4728421 | 0.77 | GABRA1 (0.56) | GABRA1GABRB2MEN1KMT2AMAPT | |
| SCHEMBL11810400 | 0.75 | GABRA1 (0.50) | GABRA1GABRB2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0383655-B1 | USE OF POLYDIORGANOSILOXANES WITH DIBENZOYLMETHANE FUNCTION IN COSMETICS AND COSMETIC COMPOSITIONS CONTAINING THESE COMPOUNDS FOR THE PROTECTION OF HAIR AND SKIN | L'OREAL (FR) | 1993-04-28 | — | — | EP | claimed |
| US-5145662-A | Ujv rad filters | L'OREAL (FR) | 1992-09-08 | — | — | US | claimed |
| US-5025053-A | Diorganopolysiloxanes containing dibenzoylmethane functional groups | RHONE-POULENC CHIMIE (FR) | 1991-06-18 | — | — | US | disclosed |