Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL680147 | 0.89 | GABRA1 (0.61) | GABRA1GABRB2KDM4EMAPTMEN1 | |
| SCHEMBL30560007 | 0.87 | AKR1C3 (0.50) | GABRA1GABRB2KDM4EMAPTAKR1C3 | |
| SCHEMBL170063 | 0.87 | AKR1C3 (0.50) | GABRA1GABRB2KDM4EMAPTAKR1C3 | |
| SCHEMBL943893 | 0.87 | AKR1C3 (0.50) | GABRA1GABRB2KDM4EMAPTAKR1C3 | |
| SCHEMBL11854227 | 0.87 | GABRA1 (0.49) | GABRA1GABRB2KDM4EMAPTMEN1 | |
| Ammonia Solution, Strong SCHEMBL28897507 | 0.85 | AKR1C3 (0.48) | GABRA1GABRB2KDM4EMAPTAKR1C3 | |
| Ethylene SCHEMBL11742925 | 0.85 | AKR1C3 (0.48) | GABRA1GABRB2KDM4EMAPTAKR1C3 | |
| SCHEMBL474923 | 0.84 | AKR1C3 (0.44) | GABRA1GABRB2KDM4EMAPTMEN1 | |
| SCHEMBL9502265 | 0.84 | GABRA1 (0.49) | GABRA1GABRB2KDM4EMAPTMEN1 | |
| SCHEMBL40309 | 0.83 | GABRA1 (0.59) | GABRA1GABRB2KDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 305 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116195582-A | Stable cyclohexanedione oxime compositions | 安道麦阿甘有限公司 | 2023-06-02 | — | — | CN | claimed |
| CN-116158426-A | Stable cyclohexanedione oxime compositions | 安道麦阿甘有限公司 | 2023-05-26 | — | — | CN | claimed |
| CN-111712523-B | Ophthalmic product composition | 爱尔兰眼力健公司 | 2023-01-03 | — | — | CN | claimed |
| EP-3728339-B1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | AMO Ireland (IE) | 2022-07-06 | — | — | EP | claimed |
| US-11359031-B2 | Composition for ophthalmological products | Johnson & Johnson Surgical Vision, Inc. (US) | 2022-06-14 | — | — | US | claimed |
| EP-3728339-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | Merck Patent GmbH (DE) | 2020-10-28 | — | — | EP | claimed |
| US-20200332041-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | MERCK PATENT GMBH (DE) | 2020-10-22 | — | — | US | claimed |
| CN-111712523-A | Ophthalmic product composition | 默克专利股份有限公司 | 2020-09-25 | — | — | CN | claimed |
| CN-104871036-B | Method for making improved UV-absorbing ophthalmic lenses | 诺华股份有限公司 | 2019-12-10 | — | — | CN | claimed |
| EP-3542193-A1 | METHOD FOR MAKING OPHTHALMIC LENSES | Novartis AG (CH) | 2019-09-25 | — | — | EP | claimed |
| US-20130095235-A1 | METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES | NOVARTIS AG (CH) | 2013-04-18 | — | — | US | claimed |
| WO-2013055746-A1 | METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES BY COATING | NOVARTIS AG (CH) | 2013-04-18 | — | — | WO | claimed |
| US-8383744-B2 | Actinically-crosslinkable siloxane-containing copolymers | NOVARTIS AG (CH) | 2013-02-26 | — | — | US | claimed |
| CN-101960388-B | Semiconductor surface treatment agent composition and method for treating semiconductor surface using the same | WAKO PURE CHEM IND LTD | 2012-11-28 | — | — | CN | claimed |
| EP-2480927-A1 | PREPOLYMERS SUITABLE FOR MAKING ULTRA-VIOLET ABSORBING CONTACT LENSES | Novartis AG (CH) | 2012-08-01 | — | — | EP | claimed |
| EP-2432808-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | Novartis AG (CH) | 2012-03-28 | — | — | EP | claimed |
| WO-2011034801-A1 | PREPOLYMERS SUITABLE FOR MAKING ULTRA-VIOLET ABSORBING CONTACT LENSES | NOVARTIS AG (CH) | 2011-03-24 | — | — | WO | claimed |
| US-20110063567-A1 | PREPOLYMERS SUITABLE FOR MAKING ULTRA-VIOLET ABSORBING CONTACT LENSES | ALCON INC. (CH) | 2011-03-17 | — | — | US | claimed |
| WO-2010133680-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | NOVARTIS AG (CH) | 2010-11-25 | — | — | WO | claimed |
| US-20100296049-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | ALCON INC. (CH) | 2010-11-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100296049-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | VCL, MACF1, CFL1 | GABRA1 832/4885GABRB2 1644/4885KDM4E 2968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.