Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 10/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.58 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.58 |
| ▸ | PDE5A | O76074 | 9/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.48 |
| ▸ | PCK1 | P35558 | 3/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13986119 | 0.84 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL7393964 | 0.82 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL13986122 | 0.80 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL13986185 | 0.80 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL7396195 | 0.80 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL7502502 | 0.78 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL7436271 | 0.77 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL7395750 | 0.75 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL7397877 | 0.74 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL7397416 | 0.73 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550559-A1 | XANTHINES | Beecham Group p.l.c. (GB) | 1993-07-14 | — | — | EP | claimed |
| EP-0550559-A1 | XANTHINES | Beecham Group p.l.c. (GB) | 1993-07-14 | — | — | EP | disclosed |