Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | DNA2 | P51530 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16993596 | 0.84 | TSHR (0.61) | TSHRTDP1L3MBTL1ALOX15POLB | |
| SCHEMBL1947839 | 0.83 | TSHR (0.58) | TSHRTDP1L3MBTL1ALOX15POLB | |
| SCHEMBL31274731 | 0.81 | TSHR (0.57) | TSHRTDP1L3MBTL1ALOX15POLB | |
| SCHEMBL9500837 | 0.79 | TSHR (0.55) | TSHRTDP1L3MBTL1ALOX15POLB | |
| SCHEMBL9657601 | 0.79 | TSHR (0.55) | TSHRTDP1L3MBTL1ALOX15POLB | |
| SCHEMBL9500972 | 0.77 | TSHR (0.47) | TSHRTDP1L3MBTL1ALOX15THRB | |
| SCHEMBL9657235 | 0.77 | TSHR (0.51) | TSHRTDP1L3MBTL1ALOX15POLB | |
| SCHEMBL9499155 | 0.74 | ALOX15 (0.50) | ALOX15ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL15507331 | 0.74 | TSHR (0.65) | TSHRTDP1L3MBTL1POLBALDH1A1 | |
| SCHEMBL9499198 | 0.74 | DTYMK (0.54) | TSHRTHRBPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312922-B1 | OXETHYLSULFONYL-NITRO- OR -AMINO-BENZOIC ACIDS AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-02 | — | — | EP | disclosed |
| EP-0312922-A2 | Oxethylsulfonyl-nitro- or -amino-benzoic acids and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-26 | — | — | EP | disclosed |