SCHEMBL9499155

SCHEMBL9499155

CC(=O)S(=O)(=O)c1c(N)cccc1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.50
MMP2 P08253 1/20 0.50
G6PD P11413 1/20 0.42
CASP7 P55210 1/20 0.42
CASP6 P55212 1/20 0.42
HSD17B10 Q99714 4/20 0.41
KDM4E B2RXH2 3/20 0.41
NPC1 O15118 1/20 0.41
CASP3 P42574 1/20 0.41
RAB9A P51151 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
CDC25B P30305 1/20 0.40
ALDH1A1 P00352 4/20 0.39
MYC P01106 1/20 0.39
HPGD P15428 2/20 0.38
MAPT P10636 2/20 0.38
GAA P10253 1/20 0.38
CA12 O43570 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL524232 0.80 MMP2 (0.55) ALOX15MMP2G6PDCASP7CASP6
SCHEMBL28069384 0.80 MMP2 (0.55) ALOX15MMP2G6PDCASP7CASP6
SCHEMBL9659714 0.77 ALOX15 (0.47) ALOX15MMP2G6PDCASP7CASP6
SCHEMBL9502499 0.74 TSHR (0.58) ALOX15CASP6KDM4ECDC25BALDH1A1
SCHEMBL9659721 0.73 MMP2 (0.47) ALOX15MMP2G6PDCASP7CASP6
Anthranilic Acid SCHEMBL16116365 0.72 ALDH1A1 (0.57) ALOX15MMP2HSD17B10KDM4ENPC1
Acetic Acid SCHEMBL27738534 0.72 G6PD (0.59) ALOX15MMP2G6PDCASP7CASP6
SCHEMBL3647611 0.71 ALOX15 (0.62) ALOX15MMP2G6PDCASP7CASP6
Anthranilic Acid SCHEMBL7622147 0.71 MAPT (0.57) ALOX15MMP2HSD17B10KDM4ENPC1
Anthranilic Acid SCHEMBL1953952 0.71 MAPT (0.57) ALOX15MMP2HSD17B10KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0312922-B1 OXETHYLSULFONYL-NITRO- OR -AMINO-BENZOIC ACIDS AND PROCESS FOR THEIR PREPARATION HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-02 EP disclosed
EP-0312922-A2 Oxethylsulfonyl-nitro- or -amino-benzoic acids and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-26 EP disclosed