SCHEMBL9502509

SCHEMBL9502509

CCCCC[C@H]1CC[C@H](OC(=O)C2(C3(CCC)CCCCC3)CCCCC2)CC1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 5/20 0.38
CYP1A2 P05177 2/20 0.34
PKM P14618 1/20 0.34
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP2C19 P33261 2/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
TP53 P04637 1/20 0.32
CCR2 P41597 1/20 0.32
MAPT P10636 1/20 0.31
GPR119 Q8TDV5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10479618 0.95 NAAA (0.38) NAAACYP1A2PKMMEN1HTT
SCHEMBL9502480 0.91 CYP2C19 (0.33) NAAACYP2C19
SCHEMBL9499229 0.89 NAAA (0.36) NAAACYP1A2CYP2C19
SCHEMBL7900588 0.77 NAAA (0.40) NAAACYP1A2PKMMEN1HTT
SCHEMBL11097035 0.77 NAAA (0.43) NAAACYP1A2HTTCYP2C19MAPT
SCHEMBL7913856 0.75 NAAA (0.40) NAAACYP1A2PKMMEN1HTT
SCHEMBL10979137 0.75 NAAA (0.39) NAAACYP1A2PKMMEN1HTT
SCHEMBL10979131 0.75 NAAA (0.39) NAAACYP1A2PKMMEN1HTT
SCHEMBL10435336 0.73 CYP1A2 (0.44) NAAACYP1A2PKMMEN1HTT
SCHEMBL10434992 0.72 CYP1A2 (0.43) NAAACYP1A2PKMMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5188758-A Electrooptical display element using a supertwist liquid crystal having specified elastic constants MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1993-02-23 US disclosed
US-4871470-A LIQUID CRYSTALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-10-03 US disclosed
US-4799774-A Electrooptical display element using a supertwist liquid crystal having specified elastic constants MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-01-24 US disclosed