SCHEMBL9502520

SCHEMBL9502520

O=C(CS)OS(=O)(=O)OC(=O)CS

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27472314 0.86 TSHR (0.41) TSHRHSD17B10
SCHEMBL28171196 0.80
SCHEMBL11599171 0.71 TSHR (0.35) TSHR
SCHEMBL1072716 0.71 ALDH1A1 (0.39) TSHR
SCHEMBL31405787 0.69 TSHR (0.39) TSHRHSD17B10
SCHEMBL28033987 0.69 LDHA (0.42) TSHR
SCHEMBL6270090 0.67 TSHR (0.56) TSHRHSD17B10
SCHEMBL407915 0.67
SCHEMBL16949667 0.65 TSHR (0.38) TSHRHSD17B10
SCHEMBL9767672 0.65 MMP1 (0.43) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0331821-B1 ANTIVIRAL AGENT KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-05-19 EP disclosed
EP-0331821-A1 Antiviral agent KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-09-13 EP disclosed