Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 4/20 | 0.58 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502439 | 0.87 | MAPT (0.62) | PLK1ACAT1NR1H4TP53TSHR | |
| SCHEMBL9503267 | 0.87 | MAPT (0.60) | PLK1ACAT1NR1H4TP53TSHR | |
| SCHEMBL9365180 | 0.87 | ACAT1 (0.67) | PLK1ACAT1NR1H4MAPK1KMT2A | |
| SCHEMBL9361286 | 0.86 | ACAT1 (0.76) | PLK1ACAT1NR1H4MAPK1KMT2A | |
| SCHEMBL9502442 | 0.85 | PLK1 (0.55) | PLK1ACAT1NR1H4TP53TSHR | |
| SCHEMBL9502352 | 0.85 | ACAT1 (0.77) | PLK1ACAT1NR1H4TP53TSHR | |
| SCHEMBL2839008 | 0.82 | SMN1; SMN2 (0.66) | PLK1NR1H4TP53TSHRLMNA | |
| SCHEMBL302596 | 0.81 | MAPT (0.74) | TP53TSHRLMNAPLA2G4BMAPT | |
| SCHEMBL7171003 | 0.81 | MAPT (0.74) | TP53TSHRLMNAPLA2G4BMAPT | |
| SCHEMBL21908583 | 0.81 | MAPT (0.74) | TP53TSHRLMNAPLA2G4BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543884-A1 | BENZANILIDE DERIVATIVES AND THEIR USE AS ANTI-ATHEROSCLEROTIC AGENTS | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | claimed |
| WO-1992003408-A1 | BENZANILIDE DERIVATIVES AND THEIR USE AS ANTI-ANTHEROSCLEROTIC AGENTS | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | claimed |
| EP-0543884-A1 | BENZANILIDE DERIVATIVES AND THEIR USE AS ANTI-ATHEROSCLEROTIC AGENTS | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003408-A1 | BENZANILIDE DERIVATIVES AND THEIR USE AS ANTI-ANTHEROSCLEROTIC AGENTS | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |