Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SCN4A | P35499 | 4/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528014 | 0.83 | MAPT (0.47) | LMNACYP2C9POLBMAPTNPSR1 | |
| SCHEMBL9123017 | 0.81 | USP2 (0.47) | LMNACYP2C9MAPTNPSR1TSHR | |
| SCHEMBL23474864 | 0.79 | MAPT (0.51) | LMNAMAPTTSHRMAPK1 | |
| SCHEMBL28430598 | 0.79 | LMNA (0.64) | LMNAPTGS1CYP2C9POLBMAPT | |
| SCHEMBL20379107 | 0.78 | LMNA (0.63) | LMNASCN4APTGS1MAOACYP2C9 | |
| SCHEMBL9123715 | 0.78 | LMNA (0.63) | LMNASCN4APTGS1MAOACYP2C9 | |
| SCHEMBL9143121 | 0.78 | FFAR1 (0.50) | LMNAPTGS1MAOANQO1MAPT | |
| SCHEMBL9143127 | 0.78 | FFAR1 (0.50) | LMNAPTGS1MAOANQO1MAPT | |
| SCHEMBL6272310 | 0.76 | LMNA (0.37) | LMNAPTGS1MAOAMAPTCYP2D6 | |
| SCHEMBL7517540 | 0.75 | NQO1 (0.41) | LMNASCN4ANQO1CYP2C9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544732-A1 | IMPROVED PROCESS FOR PREPARATION OF PHOSPHORODICHLOROTHIOATES | WEHRENBERG, Peter K. (US) | 1993-06-09 | — | — | EP | disclosed |
| WO-1992003447-A1 | IMPROVED PROCESS FOR PREPARATION OF PHOSPHORODICHLOROTHIOATES | WEHRENBERG PETER K (US) | 1992-03-05 | — | — | WO | disclosed |
| US-5081272-A | PROCESS FOR PREPARATION OF PHOSPHORODICHLOROTHIOATES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-14 | — | — | US | disclosed |
| US-4727178-A | Process for preparing phosphorodichloridothiolate | STAUFFER CHEMICAL CO. (US) | 1988-02-23 | — | — | US | disclosed |
| US-4056581-A | Process for the preparation of phosphorodichloridothiolates | ROHM AND HAAS COMPANY (US) | 1977-11-01 | — | — | US | disclosed |