Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.50 |
| ▸ | SCN4A | P35499 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20379107 | 1.00 | LMNA (0.63) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL11228825 | 0.83 | LMNA (0.59) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL7688616 | 0.81 | LMNA (0.56) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL9178337 | 0.81 | LMNA (0.68) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL13385106 | 0.81 | LMNA (0.68) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL97377 | 0.81 | LMNA (0.68) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL9808111 | 0.81 | LMNA (0.56) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL9123017 | 0.80 | USP2 (0.47) | LMNACYP2D6TSHRCYP2C9CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL28834669 | 0.79 | LMNA (0.65) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL23474864 | 0.78 | MAPT (0.51) | LMNAALDH1A1SMN1; SMN2TSHRDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113045934-A | Printing ink, application thereof and preparation method of quantum dot film | TCL集团股份有限公司 | 2021-06-29 | — | — | CN | claimed |
| CN-101367778-B | Industrialized manufacturing technique for hexafluoropropylene oxide | HAITAO FANG | 2012-06-13 | — | — | CN | claimed |
| CN-101367778-A | Industrialized manufacturing technique for hexafluoropropylene oxide | HAITAO FANG (CN) | 2009-02-18 | — | — | CN | claimed |
| CN-113045934-A | Printing ink, application thereof and preparation method of quantum dot film | TCL集团股份有限公司 | 2021-06-29 | — | — | CN | disclosed |
| US-10906866-B2 | Process for the preparation of phenoxybenzamine | AUROBINDO PHARMA LTD. (IN) | 2021-02-02 | — | — | US | disclosed |
| WO-2018130942-A1 | A PROCESS FOR THE PREPARATION OF PHENOXYBENZAMINE | AUROBINDO PHARMA LIMITED (IN) | 2018-07-19 | — | — | WO | disclosed |
| WO-2018130942-A1 | A PROCESS FOR THE PREPARATION OF PHENOXYBENZAMINE | AUROBINDO PHARMA LIMITED (IN) | 2018-07-19 | — | — | WO | disclosed |
| US-9839690-B2 | Singlet oxygen-labile linkers and methods of production and use thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2017-12-12 | — | — | US | disclosed |
| US-20170014510-A1 | Singlet Oxygen-Labile Linkers and Methods of Production and Use Thereof | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2017-01-19 | — | — | US | disclosed |
| US-9393306-B2 | Singlet oxygen-labile linkers and methods of production and use thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2016-07-19 | — | — | US | disclosed |
| US-20150165026-A1 | SINGLET OXYGEN-LABILE LINKERS AND METHODS OF PRODUCTION AND USE THEREOF | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2015-06-18 | — | — | US | disclosed |
| CN-101367778-B | Industrialized manufacturing technique for hexafluoropropylene oxide | HAITAO FANG | 2012-06-13 | — | — | CN | disclosed |
| CN-101367778-A | Industrialized manufacturing technique for hexafluoropropylene oxide | HAITAO FANG (CN) | 2009-02-18 | — | — | CN | disclosed |
| US-7264960-B2 | Enzymatic resolution of propylene glycol alkyl (or aryl) ethers and ether acetates | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-09-04 | — | — | US | disclosed |
| EP-0492615-B1 | Process for producing biguanide derivative | IDEMITSU KOSAN CO (JP) | 1995-03-08 | — | — | EP | disclosed |
| US-5286905-A | Heating hydrogen halide salt of phenoxyalkylamine with dicyandiamide in paraffinic hydrocarbon solvent | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0492615-A1 | Process for producing biguanide derivative | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-07-01 | — | — | EP | disclosed |
| US-4120888-A | REACTING PHOSGENE WITH AN EPOXY | MINEREC CORPORATION (US) | 1978-10-17 | — | — | US | disclosed |
| US-4097528-A | N-(2-diphenylmethoxyethyl)-N-(1-methyl-2-phenoxyethyl)-N-methyl! amine | DOCTOR ANDREU, S.A. (ES) | 1978-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170014510-A1 | Singlet Oxygen-Labile Linkers and Methods of Production and Use Thereof | PPOX, DUOX1, PAICS | LMNA 764/4885MAOA 293/4885PTGS1 350/4885 |
| US-10906866-B2 | Process for the preparation of phenoxybenzamine | PNMT, MAOB, COMT | LMNA 1094/4885MAOA 18/4885PTGS1 724/4885 |
| US-20150165026-A1 | SINGLET OXYGEN-LABILE LINKERS AND METHODS OF PRODUCTION AND USE THEREOF | PPOX, DUOX1, PAICS | LMNA 764/4885MAOA 293/4885PTGS1 350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.