Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 2/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500955 | 0.81 | TSPO (0.43) | TSPOCRHBPCRHR2TDP1RAB9A | |
| SCHEMBL29137813 | 0.74 | MEN1 (0.40) | TSPOCRHBPCRHR2TDP1LTB4R2 | |
| SCHEMBL3095422 | 0.69 | TSPO (0.58) | TSPOCRHBPCRHR2LTB4R2RAB9A | |
| SCHEMBL5694553 | 0.69 | TSPO (0.72) | TSPOCRHBPCRHR2LTB4R2RAB9A | |
| SCHEMBL2884029 | 0.69 | CRHBP (0.53) | CRHBPCRHR2TDP1RAB9AMEN1 | |
| SCHEMBL9501324 | 0.69 | TSHR (0.46) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL12560893 | 0.69 | TSPO (0.57) | TSPOCRHBPCRHR2TDP1LTB4R2 | |
| SCHEMBL19650787 | 0.68 | TSPO (0.56) | TSPOCRHBPCRHR2LTB4R2RAB9A | |
| SCHEMBL12536635 | 0.67 | TSPO (0.55) | TSPOCRHBPCRHR2LTB4R2RAB9A | |
| SCHEMBL1927316 | 0.66 | TDP1 (0.57) | TSPOTDP1RAB9AKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1021967-C | Process for preparing quinoline derivatives | DAINIPPON PHARMACEUTICAL CO (JP) | 1993-09-01 | — | — | CN | disclosed |
| EP-0312085-B1 | NOVEL QUINOLINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND ANTIBACTERIAL AGENT CONTAINING THEM | Dainippon Pharmaceutical Co., Ltd. (JP) | 1993-05-12 | — | — | EP | disclosed |
| US-5164392-A | Active against streptococci and staphylococci | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1992-11-17 | — | — | US | disclosed |
| US-5013841-A | Oxo quinoline derivatives | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1991-05-07 | — | — | US | disclosed |
| CN-1033996-A | New quinoline and their preparation method | DAINIPPON PHARMACEUTICAL CO (JP) | 1989-07-19 | — | — | CN | disclosed |
| EP-0312085-A2 | Novel quinoline derivatives, processes for preparation thereof and antibacterial agent containing them | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-04-19 | — | — | EP | disclosed |