Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | FPR2 | P25090 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL359065 | 1.00 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL428458 | 1.00 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL359064 | 1.00 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7775372 | 1.00 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6026558 | 1.00 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6026559 | 1.00 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL15692297 | 0.92 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9073718 | 0.87 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9073717 | 0.87 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10866724 | 0.86 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072741-A1 | PRESERVATIVES FOR MOLECULAR SAMPLE ANALYSIS WITH SAMPLE COLLECTION DEVICES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2025-04-03 | — | — | WO | claimed |
| EP-4681777-A2 | PRODRUGS OF KETAMINE, COMPOSITIONS AND USES THEREOF | XWPharma Ltd. (KY) | 2026-01-21 | — | — | EP | disclosed |
| EP-3737665-B1 | PRODRUGS OF KETAMINE, COMPOSITIONS AND USES THEREOF | XWPHARMA LTD (KY) | 2026-01-07 | — | — | EP | disclosed |
| US-20250122149-A1 | KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF | XWPharma Ltd. (KY) | 2025-04-17 | — | — | US | disclosed |
| WO-2025072741-A1 | PRESERVATIVES FOR MOLECULAR SAMPLE ANALYSIS WITH SAMPLE COLLECTION DEVICES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2025-04-03 | — | — | WO | disclosed |
| US-12209060-B2 | Ketamine derivatives and compositions thereof | XWPharma Ltd. (KY) | 2025-01-28 | — | — | US | disclosed |
| CN-114805139-B | Prodrugs of ketamine, compositions and uses thereof | 凯瑞康宁生物工程（武汉）有限公司 | 2023-10-20 | — | — | CN | disclosed |
| US-20220411365-A1 | KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF | XWPharma Ltd. (KY) | 2022-12-29 | — | — | US | disclosed |
| US-11440874-B2 | Ketamine derivatives and compositions thereof | XWPharma Ltd. (KY) | 2022-09-13 | — | — | US | disclosed |
| CN-114805139-A | Prodrugs of ketamine, compositions and uses thereof | 凯瑞康宁生物工程（武汉）有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-112135812-B | Ketamine derivatives and pharmaceutical compositions thereof | 凯瑞康宁生物工程（武汉）有限公司 | 2022-01-18 | — | — | CN | disclosed |
| US-20210032199-A1 | KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF | XW LABORATORIES INC. (KY) | 2021-02-04 | — | — | US | disclosed |
| CN-112135812-A | Ketamine derivatives and pharmaceutical compositions thereof | 凯瑞康宁生物工程（武汉）有限公司 | 2020-12-25 | — | — | CN | disclosed |
| US-10836714-B2 | Ketamine derivatives and compositions thereof | XW LABORATORIES INC. (KY) | 2020-11-17 | — | — | US | disclosed |
| CN-111836798-A | Prodrugs of ketamine, compositions and uses thereof | 凯瑞康宁生物工程（武汉）有限公司 | 2020-10-27 | — | — | CN | disclosed |
| US-20200231540-A1 | KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF | XW LABORATORIES INC. (KY) | 2020-07-23 | — | — | US | disclosed |
| US-10683262-B2 | Ketamine derivatives and compositions thereof | XW LABORATORIES INC. (KY) | 2020-06-16 | — | — | US | disclosed |
| US-20190322618-A1 | KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF | XWPharma Ltd. (KY) | 2019-10-24 | — | — | US | disclosed |
| EP-0304021-B1 | ACYLAMINO ACID RACEMASE, PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 1993-04-28 | — | — | EP | disclosed |
| EP-0304021-A2 | Acylamino acid racemase, Production and use thereof | Takeda Chemical Industries, Ltd. (JP) | 1989-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12209060-B2 | Ketamine derivatives and compositions thereof | OPRK1, KCNK10, KCNK17 | ALDH1A1 2003/4885L3MBTL1 2158/4885KMT2A 361/4885 |
| US-20190322618-A1 | KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF | OPRK1, KCNK10, KCNK17 | ALDH1A1 2003/4885L3MBTL1 2158/4885KMT2A 361/4885 |
| US-20210032199-A1 | KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF | OPRK1, KCNK10, KCNK17 | ALDH1A1 2003/4885L3MBTL1 2158/4885KMT2A 361/4885 |
| US-11440874-B2 | Ketamine derivatives and compositions thereof | OPRK1, KCNK10, KCNK17 | ALDH1A1 2003/4885L3MBTL1 2158/4885KMT2A 361/4885 |
| US-10683262-B2 | Ketamine derivatives and compositions thereof | OPRK1, KCNK10, KCNK17 | ALDH1A1 2003/4885L3MBTL1 2158/4885KMT2A 361/4885 |
| US-20200231540-A1 | KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF | OPRK1, KCNK10, KCNK17 | ALDH1A1 2003/4885L3MBTL1 2158/4885KMT2A 361/4885 |
| US-20250122149-A1 | KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF | OPRK1, KCNK10, KCNK17 | ALDH1A1 2003/4885L3MBTL1 2158/4885KMT2A 361/4885 |
| US-20220411365-A1 | KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF | OPRK1, KCNK10, KCNK17 | ALDH1A1 2003/4885L3MBTL1 2158/4885KMT2A 361/4885 |
| US-10836714-B2 | Ketamine derivatives and compositions thereof | OPRK1, KCNK10, KCNK17 | ALDH1A1 2003/4885L3MBTL1 2158/4885KMT2A 361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.