Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.38 |
| ▸ | GABRP | O00591 | 4/20 | 0.38 |
| ▸ | GABRD | O14764 | 4/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.38 |
| ▸ | GABRE | P78334 | 4/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213855 | 1.00 | P2RX7 (0.47) | P2RX7GABRB3GABRA2GABRB2GABRP | |
| SCHEMBL27256966 | 0.86 | ALDH1A1 (0.44) | P2RX7GABRB3GABRA2GABRB2GABRP | |
| SCHEMBL9213953 | 0.82 | GABRB3 (0.43) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9768169 | 0.81 | GABRB3 (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9768130 | 0.80 | GABRB3 (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9768126 | 0.80 | GABRB3 (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9501521 | 0.78 | MAPT (0.40) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9218454 | 0.78 | MAPT (0.40) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9212684 | 0.77 | GABRB3 (0.40) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9717689 | 0.77 | GABRB3 (0.40) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189053-A | Insecticide, acaricide and endoparasiticide | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-02-23 | — | — | US | disclosed |
| US-5109012-A | 2-IMIDAZOL(IN)E SUBSTITUTED ARYL-1,2,3-TRIAZOLE PESTICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-04-28 | — | — | US | disclosed |
| US-5064844-A | Miticides | SCHERING AGROCHEMICALS LIMITED (GB) | 1991-11-12 | — | — | US | disclosed |