Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13352352 | 0.82 | TSHR (0.33) | CA9CA12CA1CA2OGA | |
| SCHEMBL13321156 | 0.82 | TSHR (0.33) | CA9CA12CA1CA2OGA | |
| SCHEMBL13321139 | 0.82 | TSHR (0.33) | CA9CA12CA1CA2OGA | |
| SCHEMBL12118367 | 0.78 | MMP1 (0.32) | MMP1MMP3MMP9ADAM17METAP2 | |
| SCHEMBL7215110 | 0.77 | CA9 (0.46) | CA9CA12CA1CA2MMP9 | |
| SCHEMBL3238675 | 0.77 | CA9 (0.46) | CA9CA12CA1CA2MMP9 | |
| SCHEMBL3244545 | 0.77 | CA9 (0.46) | CA9CA12CA1CA2MMP9 | |
| SCHEMBL10013536 | 0.76 | — | — | |
| SCHEMBL10231804 | 0.76 | — | — | |
| SCHEMBL7209291 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230322-B1 | 2,6-DIDEOXY-2-FLUORO-L-TALOPYRANOSE AND DERIVATES THEREOF AND THE PRODUCTION OF THESE COMPOUNDS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1993-07-21 | — | — | EP | disclosed |
| EP-0230013-B1 | NEW ANTHRACYCLINE DERIVATIVES, USES THEREOF AS ANTITUMOR AGENT AND PRODUCTION THEREOF | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1992-06-17 | — | — | EP | disclosed |
| US-5034517-A | Process for producing 2,6-dideoxy-2-fluoro-L-talopyranose | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0230013-A1 | New anthracycline derivatives, uses thereof as antitumor agent and production thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1987-07-29 | — | — | EP | disclosed |