SCHEMBL9502955

SCHEMBL9502955

C=C(C(=O)O)C(C)N1C(=O)c2ccccc2C1=O

nearest known ligand 0.69

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.63
ALDH1A1 P00352 3/20 0.53
HTT P42858 2/20 0.53
POLB P06746 3/20 0.52
NPC1 O15118 1/20 0.51
GAA P10253 1/20 0.50
KMT2A Q03164 1/20 0.50
TP53 P04637 2/20 0.49
MAPK1 P28482 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
TSHR P16473 2/20 0.49
MAPT P10636 1/20 0.49
USP2 O75604 1/20 0.48
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL478339 0.82 LMNA (0.71) LMNAALDH1A1HTTPOLBNPC1
SCHEMBL7399848 0.82 LMNA (0.71) LMNAALDH1A1HTTPOLBNPC1
SCHEMBL125972 0.82 LMNA (0.71) LMNAALDH1A1HTTPOLBNPC1
SCHEMBL29472125 0.82 LMNA (0.71) LMNAALDH1A1HTTPOLBNPC1
Hydrochloric Acid SCHEMBL6985664 0.80 LMNA (0.69) LMNAALDH1A1HTTPOLBNPC1
Hydrochloric Acid SCHEMBL7805764 0.80 LMNA (0.69) LMNAALDH1A1HTTPOLBNPC1
SCHEMBL10577708 0.80 LMNA (0.68) LMNAALDH1A1HTTPOLBNPC1
SCHEMBL10296066 0.79 LMNA (0.68) LMNAALDH1A1HTTPOLBNPC1
SCHEMBL15671603 0.79 LMNA (0.58) LMNAALDH1A1HTTPOLBNPC1
SCHEMBL8977751 0.78 LMNA (0.66) LMNAALDH1A1HTTPOLBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0355676-B1 USE OF COPOLYMERS OF HIGHER ALKYL ACRYLATES WITH N-CONTAINING OLEFINS AS LEVELLING AGENTS FOR POWDER COATINGS Henkel Kommanditgesellschaft auf Aktien (DE) 1993-04-28 EP disclosed
US-5047259-A For powder coating; long chain alkyl acrylates; solventless paint systems HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1991-09-10 US disclosed
US-5006621-A Co-polymers of long chain alkyl acrylates with N-containing olefins and their use as flow improvers for crude oils HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1991-04-09 US disclosed
EP-0355676-A2 Use of copolymers of higher alkyl acrylates with N-containing olefins as levelling agents for powder coatings Henkel Kommanditgesellschaft auf Aktien (DE) 1990-02-28 EP disclosed
EP-0334155-A1 Copolymers of long-chain alkyl acrylates with n-containing olefins, process for their preparation and their use as flow improvers in crude oils Henkel Kommanditgesellschaft auf Aktien (DE) 1989-09-27 EP disclosed