SCHEMBL950308

SCHEMBL950308

Cc1cc(Cl)cc(C(=O)NN)c1NC(=O)c1cc(C(F)(F)F)n(Cc2ncccc2Cl)n1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KLKB1 P03952 2/20 0.40
SLC2A1 P11166 3/20 0.37
SLC2A3 P11169 3/20 0.37
SLC2A4 P14672 3/20 0.37
SLC2A2 P11168 1/20 0.37
HSD17B13 Q7Z5P4 4/20 0.36
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
PTGER1 P34995 1/20 0.35
NPY5R Q15761 2/20 0.35
P2RX7 Q99572 1/20 0.34
NR2E1 Q9Y466 1/20 0.34
SLC16A3 O15427 1/20 0.34
SLC16A1 P53985 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12912229 0.93 KLKB1 (0.40) KLKB1SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL12911748 0.91 KLKB1 (0.37) KLKB1SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL12559921 0.90 SLC16A3 (0.36) KLKB1SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL27727866 0.89 KLKB1 (0.35) KLKB1SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL12528690 0.82 PTGER1 (0.44) HSD17B13ADORA2AADORA1PTGER1
SCHEMBL950506 0.77 NPC1 (0.38) KLKB1SLC2A1SLC2A3SLC2A4KDM4E
SCHEMBL28943995 0.76 SLC16A3 (0.42) KDM4EPTGER1SLC16A3SLC16A1
SCHEMBL27727864 0.76 KLKB1 (0.33) KLKB1SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL951313 0.75 KLKB1 (0.38) KLKB1KDM4EALDH1A1
SCHEMBL951062 0.73 ALDH1A1 (0.40) SLC2A1SLC2A3SLC2A4SLC2A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968573-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-28 US disclosed
EP-1937664-B1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2011-06-15 EP disclosed
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME IKEGAMI HIROSHI 2011-03-24 US disclosed
US-7867949-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-11 US disclosed
EP-2251336-A1 Hydrazide compounds as intermediates of pesticides Sumitomo Chemical Company, Limited (JP) 2010-11-17 EP disclosed
EP-2251336-A1 Hydrazide compounds as intermediates of pesticides Sumitomo Chemical Company, Limited (JP) 2010-11-17 EP disclosed
US-20100137314-A1 HARMFUL ORGANISM CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 US disclosed
US-20100099692-A1 HARMFUL ORGANISM CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-22 US disclosed
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-16 US disclosed
EP-1937664-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2008-07-02 EP disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099692-A1 HARMFUL ORGANISM CONTROL COMPOSITION UQCRC1, UQCRC2, Q6ZSR9 KLKB1 4522/4885SLC2A1 2659/4885SLC2A3 2991/4885
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME ACHE, H1-2, H1-0 KLKB1 3821/4885SLC2A1 1654/4885SLC2A3 1853/4885
US-20100137314-A1 HARMFUL ORGANISM CONTROL COMPOSITION UQCRC2, UQCRC1, UQCRB KLKB1 4292/4885SLC2A1 2363/4885SLC2A3 2785/4885
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same ACHE, DDT, CAT KLKB1 3971/4885SLC2A1 909/4885SLC2A3 1051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.