Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 10/20 | 0.58 |
| ▸ | MMP1 | P03956 | 6/20 | 0.53 |
| ▸ | MMP2 | P08253 | 3/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.40 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506995 | 1.00 | MMP3 (0.58) | MMP3MMP1MMP2CCNA2CDK2 | |
| SCHEMBL9506233 | 0.89 | MMP3 (0.71) | MMP3MMP1MMP2 | |
| SCHEMBL9506251 | 0.89 | MMP3 (0.71) | MMP3MMP1MMP2 | |
| SCHEMBL9506811 | 0.89 | MMP3 (0.51) | MMP3MMP1MMP2 | |
| SCHEMBL9503950 | 0.89 | MMP3 (0.51) | MMP3MMP1MMP2 | |
| SCHEMBL9506857 | 0.85 | MMP3 (0.56) | MMP3MMP1MMP2 | |
| SCHEMBL9506869 | 0.85 | MMP3 (0.56) | MMP3MMP1MMP2 | |
| SCHEMBL9503957 | 0.82 | MMP3 (0.52) | MMP3MMP1MMP2 | |
| SCHEMBL9503983 | 0.81 | MMP3 (0.51) | MMP3MMP1MMP2PSMB9 | |
| SCHEMBL9503972 | 0.81 | MMP3 (0.51) | MMP3MMP1MMP2PSMB9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276436-B1 | PHOSPHINIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-16 | — | — | EP | disclosed |
| US-5006651-A | Rheumatic diseases, bone disorders | HOFFMAN-LA ROCHE INC. (US) | 1991-04-09 | — | — | US | disclosed |
| US-4885283-A | Phosphinic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1989-12-05 | — | — | US | disclosed |
| EP-0276436-A1 | Phosphinic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1988-08-03 | — | — | EP | disclosed |