SCHEMBL9503179

SCHEMBL9503179

C=Cc1ccc2c([nH]c3ccccc32)c1CC(=C)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPL P40238 2/20 0.41
PIM3 Q86V86 3/20 0.39
PIM1 P11309 2/20 0.39
PIM2 Q9P1W9 1/20 0.39
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.38
GAA P10253 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
PARP14 Q460N5 2/20 0.38
EGFR P00533 2/20 0.37
KIF11 P52732 1/20 0.37
GABRP O00591 1/20 0.36
GABRD O14764 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRB1 P18505 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRA5 P31644 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8095424 0.78 ALDH1A1 (0.43) PIM3PIM1PIM2KDM4EALDH1A1
SCHEMBL2139000 0.77 KIF11 (0.44) PIM3PIM1PIM2KDM4EALDH1A1
SCHEMBL208867 0.76 KDM4E (0.45) KDM4EALDH1A1MAPTGAAHTT
SCHEMBL9503175 0.72 PIM3 (0.39) MPLPIM3PIM1PIM2KDM4E
Benzene SCHEMBL26657973 0.72 KIF11 (0.47) MPLPIM3PIM1PIM2KDM4E
SCHEMBL9502084 0.72 PIM3 (0.44) MPLPIM3PIM1PIM2KDM4E
Pavettine SCHEMBL27508629 0.72 KIF11 (0.55) PIM3PIM1PIM2KDM4EALDH1A1
Pavettine SCHEMBL36138 0.71 KIF11 (0.53) PIM3PIM1PIM2KDM4EALDH1A1
Pavettine SCHEMBL29450528 0.71 KIF11 (0.53) PIM3PIM1PIM2KDM4EALDH1A1
Pavettine SCHEMBL28686824 0.71 KIF11 (0.53) PIM3PIM1PIM2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0235038-B1 VISIBLE-RAY RECORDING HOLOGRAM MATERIAL FUJITSU LIMITED (JP) 1993-05-26 EP claimed