Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 9/20 | 0.56 |
| ▸ | ANPEP | P15144 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14561134 | 1.00 | MMP2 (0.56) | MMP2ANPEPALDH1A1KMT2AMMP1 | |
| SCHEMBL9503995 | 1.00 | MMP2 (0.56) | MMP2ANPEPALDH1A1KMT2AMMP1 | |
| SCHEMBL5397377 | 0.89 | CA12 (0.47) | MMP2ANPEPALDH1A1KMT2AMMP1 | |
| SCHEMBL5397387 | 0.89 | CA12 (0.47) | MMP2ANPEPALDH1A1KMT2AMMP1 | |
| SCHEMBL5397381 | 0.89 | CA12 (0.47) | MMP2ANPEPALDH1A1KMT2AMMP1 | |
| SCHEMBL7142526 | 0.87 | MME (0.46) | MMP2ANPEPALDH1A1KMT2A | |
| SCHEMBL7152576 | 0.87 | MME (0.46) | MMP2ANPEPALDH1A1KMT2A | |
| SCHEMBL9505317 | 0.85 | MMP2 (0.61) | MMP2ANPEPALDH1A1KMT2AMMP1 | |
| SCHEMBL5418223 | 0.85 | MMP2 (0.61) | MMP2ANPEPALDH1A1KMT2AMMP1 | |
| SCHEMBL17833288 | 0.85 | MMP2 (0.61) | MMP2ANPEPALDH1A1KMT2AMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289911-B1 | PYRROLIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-4916152-A | THROMBOXANE A2 ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |
| EP-0289911-A2 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-09 | — | — | EP | disclosed |