Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5397387 | 1.00 | CA12 (0.47) | CA12CA1CA2CA9MMP2 | |
| SCHEMBL5397377 | 1.00 | CA12 (0.47) | CA12CA1CA2CA9MMP2 | |
| SCHEMBL9503221 | 0.89 | MMP2 (0.56) | CA12CA1CA2CA9MMP2 | |
| SCHEMBL9503995 | 0.89 | MMP2 (0.56) | CA12CA1CA2CA9MMP2 | |
| SCHEMBL14561134 | 0.89 | MMP2 (0.56) | CA12CA1CA2CA9MMP2 | |
| SCHEMBL6860718 | 0.87 | AKR1C3 (0.48) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL5497274 | 0.80 | MMP2 (0.53) | CA12CA1CA2CA9MMP2 | |
| SCHEMBL5497267 | 0.80 | MMP2 (0.53) | CA12CA1CA2CA9MMP2 | |
| SCHEMBL5497278 | 0.80 | MMP2 (0.53) | CA12CA1CA2CA9MMP2 | |
| SCHEMBL17822348 | 0.80 | MMP2 (0.53) | CA12CA1CA2CA9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196112-B2 | Cell adhesion inhibitors | BIOGEN IDEC MA INC. (US) | 2007-03-27 | — | — | US | disclosed |
| US-20070066533-A1 | Cell adhesion inhibitors | LEE WEN-CHERNG | 2007-03-22 | — | — | US | disclosed |
| US-20060014966-A1 | Cell adhesion inhibitors | BIOGEN IDEC MA INC. | 2006-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066533-A1 | Cell adhesion inhibitors | VCAM1, EPCAM, ICAM1 | CA12 2477/4885CA1 2937/4885CA2 4147/4885 |
| US-20060014966-A1 | Cell adhesion inhibitors | VCAM1, EPCAM, ICAM1 | CA12 2477/4885CA1 2937/4885CA2 4147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.