SCHEMBL9503285

SCHEMBL9503285

CCCCCCCCCCCCCCCCCC(=O)Oc1ccc(C(OC(=O)CCCCCCCCCCCCCCCCC)(c2ccccc2)c2ccccc2)c(OC(=O)CCCCCCCCCCCCCCCCC)c1OC(=O)CCCCCCCCCCCCCCCCC

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
RECQL P46063 1/20 0.45
KMT2A Q03164 1/20 0.45
POLM Q9NP87 2/20 0.42
POLK Q9UBT6 2/20 0.42
POLL Q9UGP5 2/20 0.42
POLH Q9Y253 2/20 0.42
ALOX15 P16050 1/20 0.42
TOP2A P11388 2/20 0.39
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
EPHX2 P34913 1/20 0.38
PPARG P37231 1/20 0.38
PTPN1 P18031 1/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28469181 0.82 CES2 (0.49) KDM4EMEN1RECQLKMT2AEPHX2
SCHEMBL17138174 0.75 POLM (0.62) KDM4EMEN1RECQLKMT2APOLM
SCHEMBL29371710 0.74 EPHX2 (0.51) KDM4EMEN1RECQLKMT2APOLM
SCHEMBL29372133 0.74 EPHX2 (0.51) KDM4EMEN1RECQLKMT2APOLM
SCHEMBL30003164 0.74 EPHX2 (0.51) KDM4EMEN1RECQLKMT2APOLM
SCHEMBL23271733 0.74 EPHX2 (0.51) KDM4EMEN1RECQLKMT2APOLM
SCHEMBL20398624 0.74 EPHX2 (0.51) KDM4EMEN1RECQLKMT2APOLM
SCHEMBL20398590 0.74 EPHX2 (0.51) KDM4EMEN1RECQLKMT2APOLM
SCHEMBL20398671 0.74 EPHX2 (0.51) KDM4EMEN1RECQLKMT2APOLM
SCHEMBL29368355 0.74 EPHX2 (0.51) KDM4EMEN1RECQLKMT2APOLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0320826-B1 RUBBER-COATED GASKET NICHIAS CORPORATION (JP) 1993-05-19 EP claimed